FAM27E2

Summary

FAM27E2 (family with sequence similarity 27 member E2, HGNC:32013) is a long non-coding RNA gene on chromosome 9p11.2.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32013
Approved symbol	FAM27E2
Name	family with sequence similarity 27 member E2
Location	9p11.2
Locus type	RNA, long non-coding
Status	Approved
Entrez	100289124
RNAcentral	URS000075C6C7 — lncRNA, 1767 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1001143359 (9:41648431 T>C), RS1002599150 (9:41649325 GATAATA>G,GATA), RS1006553948 (9:41647239 A>C), RS1008807010 (9:41646180 G>A,T), RS1010309713 (9:41649075 T>C), RS1018412737 (9:41646209 G>A,C,T), RS1019913293 (9:41649131 A>G), RS1020450947 (9:41646964 G>A), RS1025540694 (9:41647257 G>A,C), RS1032689794 (9:41646630 AC>A), RS1034175505 (9:41649668 T>G), RS1038354353 (9:41645703 C>A,G,T), RS1039911708 (9:41647886 T>G), RS1046854 (9:41649136 C>A,T), RS1047179598 (9:41647540 G>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.