FAM27E5

Summary

FAM27E5 (family with sequence similarity E5, HGNC:32410) is a long non-coding RNA gene on chromosome 17p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32410
Approved symbol	FAM27E5
Name	family with sequence similarity E5
Location	17p11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC35151
Ensembl gene	ENSG00000178130
Ensembl biotype	lncRNA
Entrez	284123
RNAcentral	URS000075CD4C — lncRNA, 609 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000426869, ENST00000613377

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000426869 — 2 exons

Exon	Start	End
ENSE00004154248	22299490	22300066
ENSE00004154249	22298691	22298968

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 63.29.

Top tissues by expression

35 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ventricular zone	UBERON:0003053	63.29	gold quality
right lobe of liver	UBERON:0001114	59.22	gold quality
cortical plate	UBERON:0005343	58.59	gold quality
left coronary artery	UBERON:0001626	55.62	gold quality
placenta	UBERON:0001987	55.18	gold quality
spleen	UBERON:0002106	53.38	gold quality
right hemisphere of cerebellum	UBERON:0014890	53.02	gold quality
tibial artery	UBERON:0007610	52.86	gold quality
ascending aorta	UBERON:0001496	52.74	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	52.57	gold quality
blood	UBERON:0000178	52.53	gold quality
anterior cingulate cortex	UBERON:0009835	51.95	gold quality
sural nerve	UBERON:0015488	51.27	silver quality
thoracic aorta	UBERON:0001515	51.26	gold quality
left lobe of thyroid gland	UBERON:0001120	51.21	gold quality
body of pancreas	UBERON:0001150	50.96	gold quality
adrenal gland	UBERON:0002369	50.84	gold quality
heart left ventricle	UBERON:0002084	50.17	gold quality
monocyte	CL:0000576	49.96	silver quality
cerebellar hemisphere	UBERON:0002245	49.93	gold quality
hypothalamus	UBERON:0001898	49.41	gold quality
gastrocnemius	UBERON:0001388	48.37	gold quality
nucleus accumbens	UBERON:0001882	47.91	gold quality
cerebral cortex	UBERON:0000956	47.66	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	46.41	gold quality
tibial nerve	UBERON:0001323	44.92	silver quality
right frontal lobe	UBERON:0002810	38.81	gold quality
right atrium auricular region	UBERON:0006631	38.05	silver quality
skin of abdomen	UBERON:0001416	37.86	silver quality
multicellular organism	UBERON:0000468	37.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.41

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.