FAM41AY2

Summary

FAM41AY2 (family with sequence similarity 41 member A, Y-linked 2, HGNC:37135) is a long non-coding RNA gene on chromosome Yq11.222.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37135
Approved symbol	FAM41AY2
Name	family with sequence similarity 41 member A, Y-linked 2
Location	Yq11.222
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226362
Entrez	100302526
RNAcentral	URS000075D2EE — lncRNA, 2043 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Bgee: expression breadth tissue_specific, 1 present calls, max score 25.48.

Top tissues by expression

1 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
testis	UBERON:0000473	25.48	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 1 (showing top): chrYq11

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 93 via entrez): RS112215124 (Y:18406450 G>A), RS1164345204 (Y:18392727 C>A), RS1309533696 (Y:18406679 G>A), RS1353208846 (Y:18406686 G>A), RS1365771958 (Y:18392526 T>C), RS1395251574 (Y:18392870 G>C), RS1396315934 (Y:18395771 G>T), RS1463525319 (Y:18392979 A>C), RS1474312440 (Y:18392625 C>G), RS1556287463 (Y:18391944 T>C), RS1556287498 (Y:18403562 A>G), RS1603535374 (Y:18392175 T>C), RS1603535375 (Y:18392249 T>G), RS1603535376 (Y:18392288 A>G), RS1603535377 (Y:18392310 T>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.