FAM66A

Summary

FAM66A (family with sequence similarity 66 member A, HGNC:30444) is a long non-coding RNA gene on chromosome 8p23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30444
Approved symbol	FAM66A
Name	family with sequence similarity 66 member A
Location	8p23.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227888
Ensembl biotype	lncRNA
Entrez	100133172
RNAcentral	URS000075E73C — lncRNA, 775 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 411 — 411 lncRNA

ENST00000525829, ENST00000602658, ENST00000602979, ENST00000744306, ENST00000744307, ENST00000744308, ENST00000744309, ENST00000744310, ENST00000744311, ENST00000744312, ENST00000744313, ENST00000744314, ENST00000744315, ENST00000744316, ENST00000744317, ENST00000744318, ENST00000744319, ENST00000744320, ENST00000744321, ENST00000744322, ENST00000744323, ENST00000744324, ENST00000744325, ENST00000744326, ENST00000744327, ENST00000744328, ENST00000744329, ENST00000744330, ENST00000744331, ENST00000744332, ENST00000744333, ENST00000744334, ENST00000744335, ENST00000744336, ENST00000744337, ENST00000744338, ENST00000744339, ENST00000744340, ENST00000744341, ENST00000744342, ENST00000744343, ENST00000744344, ENST00000744345, ENST00000744346, ENST00000744347, ENST00000744348, ENST00000744349, ENST00000744350, ENST00000744351, ENST00000744352, ENST00000744353, ENST00000744354, ENST00000744355, ENST00000744356, ENST00000744357, ENST00000744358, ENST00000744359, ENST00000744360, ENST00000744361, ENST00000744362, ENST00000744363, ENST00000744364, ENST00000744365, ENST00000744366, ENST00000744367, ENST00000744368, ENST00000744369, ENST00000744370, ENST00000744371, ENST00000744372, ENST00000744373, ENST00000744374, ENST00000744375, ENST00000744376, ENST00000744377, ENST00000744378, ENST00000744379, ENST00000744380, ENST00000744381, ENST00000744382, ENST00000744383, ENST00000744384, ENST00000744385, ENST00000744386, ENST00000744387, ENST00000744388, ENST00000744389, ENST00000744390, ENST00000744391, ENST00000744392, ENST00000744393, ENST00000744394, ENST00000744395, ENST00000744396, ENST00000744397, ENST00000744398, ENST00000744399, ENST00000744400, ENST00000744401, ENST00000744402, ENST00000744403, ENST00000744404, ENST00000744405, ENST00000744406, ENST00000744407, ENST00000744408, ENST00000744409, ENST00000744410, ENST00000744411, ENST00000744412, ENST00000744413, ENST00000744414, ENST00000744415, ENST00000744416, ENST00000744417, ENST00000744418, ENST00000744419, ENST00000744420, ENST00000744421, ENST00000744422, ENST00000744423, ENST00000744424, ENST00000744425, ENST00000744426, ENST00000744427, ENST00000744428, ENST00000744429, ENST00000744430, ENST00000744431, ENST00000744432, ENST00000744433, ENST00000744434, ENST00000744435, ENST00000744436, ENST00000744437, ENST00000744438, ENST00000744439, ENST00000744440, ENST00000744441, ENST00000744442, ENST00000744443, ENST00000744444, ENST00000744445, ENST00000744446, ENST00000744447, ENST00000744448, ENST00000744449, ENST00000744450, ENST00000744451, ENST00000744452, ENST00000744453, ENST00000744454, ENST00000744455, ENST00000744456, ENST00000744457, ENST00000744458, ENST00000744459, ENST00000744460, ENST00000744461, ENST00000744462, ENST00000744463, ENST00000744464, ENST00000744465, ENST00000744466, ENST00000744467, ENST00000744468, ENST00000744469, ENST00000744470, ENST00000744471, ENST00000744472, ENST00000744473, ENST00000744474, ENST00000744475, ENST00000744476, ENST00000744477, ENST00000744478, ENST00000744479, ENST00000744480, ENST00000744481, ENST00000744482, ENST00000744483, ENST00000744484, ENST00000744485, ENST00000744486, ENST00000744487, ENST00000744488, ENST00000744489, ENST00000744490, ENST00000744491, ENST00000744492, ENST00000744493, ENST00000744494, ENST00000744495, ENST00000744496, ENST00000744497, ENST00000744498, ENST00000744499, ENST00000744500, ENST00000744501, ENST00000744502, ENST00000744503, ENST00000744504, ENST00000744505, ENST00000744506, ENST00000744507, ENST00000744508, ENST00000744509, ENST00000744510, ENST00000744511, ENST00000744512, ENST00000744513, ENST00000744514, ENST00000744515, ENST00000744516, ENST00000744517, ENST00000744518, ENST00000744519, ENST00000744520, ENST00000744521, ENST00000744522, ENST00000744523, ENST00000744524, ENST00000744525, ENST00000744526, ENST00000744527, ENST00000744528, ENST00000744529, ENST00000744530, ENST00000744531, ENST00000744532, ENST00000744533, ENST00000744534, ENST00000744535, ENST00000744536, ENST00000744537, ENST00000744538, ENST00000744539, ENST00000744540, ENST00000744541, ENST00000744542, ENST00000744543, ENST00000744544, ENST00000744545, ENST00000744546, ENST00000744547, ENST00000744548, ENST00000744549, ENST00000744550, ENST00000744551, ENST00000744552, ENST00000744553, ENST00000744554, ENST00000744555, ENST00000744556, ENST00000744557, ENST00000744558, ENST00000744559, ENST00000744560, ENST00000744561, ENST00000744562, ENST00000744563, ENST00000744564, ENST00000744565, ENST00000744566, ENST00000744567, ENST00000744568, ENST00000744569, ENST00000744570, ENST00000744571, ENST00000744572, ENST00000744573, ENST00000744574, ENST00000744575, ENST00000744576, ENST00000744577, ENST00000744578, ENST00000744579, ENST00000744580, ENST00000744581, ENST00000744582, ENST00000744583, ENST00000744584, ENST00000744585, ENST00000744586, ENST00000744587, ENST00000744588, ENST00000744589, ENST00000744590, ENST00000744591, ENST00000744592, ENST00000744593, ENST00000744594, ENST00000744595, ENST00000744596, ENST00000744597, ENST00000744598, ENST00000744599, ENST00000744600, ENST00000744601, ENST00000744602, ENST00000744603, ENST00000744604, ENST00000744605, ENST00000744606, ENST00000744607, ENST00000744608, ENST00000744609, ENST00000744610, ENST00000744611, ENST00000744612, ENST00000744613, ENST00000744614, ENST00000744615, ENST00000744616, ENST00000744617, ENST00000744618, ENST00000744619, ENST00000744620, ENST00000744621, ENST00000744622, ENST00000744623, ENST00000744624, ENST00000744625, ENST00000744626, ENST00000744627, ENST00000744628, ENST00000744629, ENST00000744630, ENST00000744631, ENST00000744632, ENST00000744633, ENST00000744634, ENST00000744635, ENST00000744636, ENST00000744637, ENST00000744638, ENST00000744639, ENST00000744640, ENST00000744641, ENST00000744642, ENST00000744643, ENST00000744644, ENST00000744645, ENST00000744646, ENST00000744647, ENST00000744648, ENST00000744649, ENST00000744650, ENST00000744651, ENST00000744652, ENST00000744653, ENST00000744654, ENST00000744655, ENST00000744656, ENST00000744657, ENST00000744658, ENST00000744659, ENST00000744660, ENST00000744661, ENST00000744662, ENST00000744663, ENST00000744664, ENST00000744665, ENST00000744666, ENST00000744667, ENST00000744668, ENST00000744669, ENST00000744670, ENST00000744671, ENST00000744672, ENST00000744673, ENST00000744674, ENST00000744675, ENST00000744676, ENST00000744677, ENST00000744678, ENST00000744679, ENST00000744680, ENST00000744681, ENST00000744682, ENST00000744683, ENST00000744684, ENST00000744685, ENST00000744686, ENST00000744687, ENST00000744688, ENST00000744689, ENST00000744690, ENST00000744691, ENST00000744692, ENST00000744693, ENST00000744694, ENST00000744695, ENST00000744696, ENST00000744697, ENST00000744698, ENST00000744699, ENST00000744700, ENST00000744701, ENST00000744702, ENST00000744703, ENST00000744704, ENST00000744705, ENST00000744706, ENST00000744707, ENST00000744708, ENST00000744709, ENST00000744710, ENST00000744711, ENST00000744712, ENST00000744713

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000525829 — 2 exons

Exon	Start	End
ENSE00004083762	12368239	12369730
ENSE00004083796	12362019	12362562

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 91.79.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.90	gold quality
cortical plate	UBERON:0005343	75.82	gold quality
ventricular zone	UBERON:0003053	72.63	gold quality
ganglionic eminence	UBERON:0004023	71.16	gold quality
sural nerve	UBERON:0015488	70.83	gold quality
bone marrow cell	CL:0002092	67.97	silver quality
colonic epithelium	UBERON:0000397	67.41	silver quality
primary visual cortex	UBERON:0002436	66.64	gold quality
prefrontal cortex	UBERON:0000451	66.53	gold quality
superior frontal gyrus	UBERON:0002661	66.29	gold quality
frontal cortex	UBERON:0001870	65.46	gold quality
anterior cingulate cortex	UBERON:0009835	65.08	gold quality
caudate nucleus	UBERON:0001873	64.98	gold quality
nucleus accumbens	UBERON:0001882	64.60	gold quality
temporal lobe	UBERON:0001871	64.53	gold quality
cerebral cortex	UBERON:0000956	64.38	gold quality
amygdala	UBERON:0001876	64.33	gold quality
hypothalamus	UBERON:0001898	64.03	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	63.87	gold quality
brain	UBERON:0000955	63.64	gold quality
bone marrow	UBERON:0002371	63.60	silver quality
right frontal lobe	UBERON:0002810	63.30	gold quality
stromal cell of endometrium	CL:0002255	63.23	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.17	gold quality
skeletal muscle tissue	UBERON:0001134	62.35	gold quality
right coronary artery	UBERON:0001625	62.24	gold quality
putamen	UBERON:0001874	62.01	gold quality
cerebellum	UBERON:0002037	62.00	gold quality
Brodmann (1909) area 9	UBERON:0013540	61.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.