FAM66D

Summary

FAM66D (family with sequence similarity 66 member D, HGNC:24159) is a long non-coding RNA gene on chromosome 8p23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:24159
Approved symbol	FAM66D
Name	family with sequence similarity 66 member D
Location	8p23.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255052
Ensembl biotype	lncRNA
Entrez	100132923
RNAcentral	URS000075BC0D — lncRNA, 1071 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000434078, ENST00000653269, ENST00000653408, ENST00000653486, ENST00000653725, ENST00000654985, ENST00000656282, ENST00000658322, ENST00000665207, ENST00000666028, ENST00000666566, ENST00000669660, ENST00000670188, ENST00000715432, ENST00000715433, ENST00000715434, ENST00000715435

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434078 — 4 exons

Exon	Start	End
ENSE00002256766	12115782	12116325
ENSE00002276897	12145639	12145700
ENSE00003745833	12176823	12176965
ENSE00003748962	12177382	12177550

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 87.08.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.08	gold quality
corpus callosum	UBERON:0002336	81.91	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.31	gold quality
cortical plate	UBERON:0005343	78.35	gold quality
stromal cell of endometrium	CL:0002255	76.29	gold quality
superior frontal gyrus	UBERON:0002661	76.11	gold quality
nucleus accumbens	UBERON:0001882	75.90	gold quality
caudate nucleus	UBERON:0001873	74.76	gold quality
temporal lobe	UBERON:0001871	74.51	gold quality
amygdala	UBERON:0001876	74.49	gold quality
ventricular zone	UBERON:0003053	74.33	gold quality
putamen	UBERON:0001874	73.95	gold quality
hypothalamus	UBERON:0001898	73.72	gold quality
pituitary gland	UBERON:0000007	73.68	gold quality
right frontal lobe	UBERON:0002810	73.66	gold quality
frontal cortex	UBERON:0001870	73.53	gold quality
brain	UBERON:0000955	73.38	gold quality
left ovary	UBERON:0002119	73.19	gold quality
prefrontal cortex	UBERON:0000451	73.10	gold quality
anterior cingulate cortex	UBERON:0009835	72.94	gold quality
cerebral cortex	UBERON:0000956	72.92	gold quality
adenohypophysis	UBERON:0002196	72.69	gold quality
primary visual cortex	UBERON:0002436	72.51	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	72.31	gold quality
ganglionic eminence	UBERON:0004023	72.27	gold quality
ovary	UBERON:0000992	72.24	gold quality
substantia nigra	UBERON:0002038	72.22	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	72.05	gold quality
Ammon’s horn	UBERON:0001954	71.73	gold quality
right uterine tube	UBERON:0001302	71.56	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.