FAM74A1

Summary

FAM74A1 (family with sequence similarity 74 member A1, HGNC:32029) is a long non-coding RNA gene on chromosome 9p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32029
Approved symbol	FAM74A1
Name	family with sequence similarity 74 member A1
Location	9p12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000215112
Ensembl biotype	lncRNA
Entrez	401507
RNAcentral	URS000048B537 — lncRNA, 623 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000465257, ENST00000597685, ENST00000833440, ENST00000833441, ENST00000833442, ENST00000833443

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000465257 — 2 exons

Exon	Start	End
ENSE00004250007	39376840	39377520
ENSE00004250013	39371035	39371610

Expression profiles

Bgee: expression breadth broad, 84 present calls, max score 97.20.

Top tissues by expression

84 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	97.20	gold quality
tonsil	UBERON:0002372	68.45	gold quality
sural nerve	UBERON:0015488	65.81	gold quality
left testis	UBERON:0004533	63.47	gold quality
right testis	UBERON:0004534	62.60	gold quality
testis	UBERON:0000473	62.52	gold quality
calcaneal tendon	UBERON:0003701	60.59	gold quality
pancreas	UBERON:0001264	59.50	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.89	gold quality
liver	UBERON:0002107	58.76	gold quality
endometrium	UBERON:0001295	58.41	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.73	gold quality
bone marrow	UBERON:0002371	57.58	gold quality
monocyte	CL:0000576	56.67	gold quality
temporal lobe	UBERON:0001871	56.41	gold quality
blood	UBERON:0000178	56.32	gold quality
right lobe of liver	UBERON:0001114	56.31	gold quality
amygdala	UBERON:0001876	56.03	gold quality
duodenum	UBERON:0002114	55.81	gold quality
caudate nucleus	UBERON:0001873	55.71	gold quality
hypothalamus	UBERON:0001898	54.79	gold quality
Ammon’s horn	UBERON:0001954	54.03	gold quality
urinary bladder	UBERON:0001255	53.45	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.88	gold quality
nucleus accumbens	UBERON:0001882	52.65	gold quality
vermiform appendix	UBERON:0001154	51.76	gold quality
cortex of kidney	UBERON:0001225	51.69	silver quality
multicellular organism	UBERON:0000468	51.06	gold quality
body of pancreas	UBERON:0001150	50.98	gold quality
smooth muscle tissue	UBERON:0001135	50.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.