FAM74A3

Summary

FAM74A3 (family with sequence similarity 74 member A3, HGNC:32031) is a long non-coding RNA gene on chromosome 9q21.11.

At a glance

• Gene type: non-coding (transcribed_processed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32031
Approved symbol	FAM74A3
Name	family with sequence similarity 74 member A3
Location	9q21.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	OTTHUMG00000067149
Ensembl gene	ENSG00000274355
Ensembl biotype	transcribed_processed_pseudogene
Entrez	728495
RNAcentral	URS000075DBA9 — lncRNA, 1883 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_processed_pseudogene

ENST00000620271

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000620271 — 1 exons

Exon	Start	End
ENSE00003746044	66976520	66976991

Expression profiles

Bgee: expression breadth broad, 54 present calls, max score 43.75.

Top tissues by expression

109 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	43.75	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	43.20	gold quality
calcaneal tendon	UBERON:0003701	39.84	gold quality
ventricular zone	UBERON:0003053	36.48	gold quality
cortical plate	UBERON:0005343	36.47	gold quality
bone marrow cell	CL:0002092	36.16	gold quality
hypothalamus	UBERON:0001898	35.85	gold quality
left uterine tube	UBERON:0001303	35.63	silver quality
ganglionic eminence	UBERON:0004023	35.49	gold quality
smooth muscle tissue	UBERON:0001135	34.33	gold quality
muscle tissue	UBERON:0002385	33.61	gold quality
skeletal muscle tissue	UBERON:0001134	33.38	gold quality
caudate nucleus	UBERON:0001873	32.54	gold quality
rectum	UBERON:0001052	32.30	gold quality
fallopian tube	UBERON:0003889	32.30	gold quality
hindlimb stylopod muscle	UBERON:0004252	32.15	gold quality
Ammon’s horn	UBERON:0001954	32.04	gold quality
placenta	UBERON:0001987	31.94	gold quality
bone marrow	UBERON:0002371	31.74	gold quality
sural nerve	UBERON:0015488	30.93	gold quality
gall bladder	UBERON:0002110	30.46	gold quality
stromal cell of endometrium	CL:0002255	29.87	gold quality
right lobe of liver	UBERON:0001114	29.79	silver quality
temporal lobe	UBERON:0001871	29.42	gold quality
amygdala	UBERON:0001876	29.38	gold quality
prefrontal cortex	UBERON:0000451	29.31	gold quality
duodenum	UBERON:0002114	28.14	gold quality
left testis	UBERON:0004533	27.75	silver quality
lymph node	UBERON:0000029	27.57	gold quality
urinary bladder	UBERON:0001255	27.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.