FAM87A

Summary

FAM87A (family with sequence similarity 87 member A, HGNC:27233) is a long non-coding RNA gene on chromosome 8p23.3.

Predicted to be located in membrane.

Source: NCBI Gene 157693 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27233
Approved symbol	FAM87A
Name	family with sequence similarity 87 member A
Location	8p23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000182366
Ensembl biotype	lncRNA
Entrez	157693
RNAcentral	URS000075D985 — lncRNA, 4028 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000330148, ENST00000523195, ENST00000602608, ENST00000658419, ENST00000662707, ENST00000668758, ENST00000758787, ENST00000758788, ENST00000758789, ENST00000758790

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000330148 — 4 exons

Exon	Start	End
ENSE00001306277	377564	380309
ENSE00001693634	375931	377045
ENSE00003271556	383060	383174
ENSE00003362255	381156	381192

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 81.14.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.14	gold quality
bone marrow cell	CL:0002092	70.91	gold quality
bone marrow	UBERON:0002371	66.47	gold quality
primary visual cortex	UBERON:0002436	64.34	gold quality
prefrontal cortex	UBERON:0000451	62.15	gold quality
superior frontal gyrus	UBERON:0002661	62.13	gold quality
ventricular zone	UBERON:0003053	62.04	gold quality
body of pancreas	UBERON:0001150	62.01	gold quality
cortical plate	UBERON:0005343	61.50	silver quality
colonic epithelium	UBERON:0000397	61.04	silver quality
frontal cortex	UBERON:0001870	60.84	gold quality
pancreas	UBERON:0001264	60.57	gold quality
ganglionic eminence	UBERON:0004023	59.46	gold quality
right frontal lobe	UBERON:0002810	58.79	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	58.20	gold quality
Brodmann (1909) area 9	UBERON:0013540	57.61	gold quality
lymph node	UBERON:0000029	57.39	gold quality
islet of Langerhans	UBERON:0000006	57.37	gold quality
tonsil	UBERON:0002372	57.29	gold quality
cerebral cortex	UBERON:0000956	56.94	gold quality
skeletal muscle tissue	UBERON:0001134	56.53	gold quality
right coronary artery	UBERON:0001625	56.11	gold quality
leukocyte	CL:0000738	54.70	gold quality
monocyte	CL:0000576	54.03	gold quality
stromal cell of endometrium	CL:0002255	53.93	silver quality
blood	UBERON:0000178	53.53	silver quality
right uterine tube	UBERON:0001302	53.18	gold quality
duodenum	UBERON:0002114	52.99	gold quality
placenta	UBERON:0001987	52.64	gold quality
urinary bladder	UBERON:0001255	52.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.41

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.