FAM88B

Summary

FAM88B (family with sequence similarity 88 member B, HGNC:31457) is a long non-coding RNA gene on chromosome 9q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31457
Approved symbol	FAM88B
Name	family with sequence similarity 88 member B
Location	9q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000170161
Ensembl biotype	lncRNA
Entrez	728673
RNAcentral	URS00007E4EDE — lncRNA, 2259 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 56 — 56 lncRNA

ENST00000305709, ENST00000467494, ENST00000476224, ENST00000655734, ENST00000661415, ENST00000671425, ENST00000848707, ENST00000848708, ENST00000848709, ENST00000848710, ENST00000848711, ENST00000848712, ENST00000848713, ENST00000848714, ENST00000848715, ENST00000848716, ENST00000848717, ENST00000848718, ENST00000848719, ENST00000848720, ENST00000848721, ENST00000848722, ENST00000848723, ENST00000848724, ENST00000848725, ENST00000848726, ENST00000848727, ENST00000848728, ENST00000848729, ENST00000848730, ENST00000848731, ENST00000848732, ENST00000848733, ENST00000848734, ENST00000848735, ENST00000848736, ENST00000848737, ENST00000848738, ENST00000848739, ENST00000848740, ENST00000848741, ENST00000848742, ENST00000848743, ENST00000848744, ENST00000848745, ENST00000848746, ENST00000848747, ENST00000848748, ENST00000848749, ENST00000848750, ENST00000848751, ENST00000848752, ENST00000848753, ENST00000848754, ENST00000848755, ENST00000848756

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000305709 — 2 exons

Exon	Start	End
ENSE00004278489	62897349	62897734
ENSE00004278490	62897850	62900104

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 85.06.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.06	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.07	gold quality
bone marrow cell	CL:0002092	81.62	gold quality
ventricular zone	UBERON:0003053	80.34	gold quality
ganglionic eminence	UBERON:0004023	80.20	gold quality
colonic epithelium	UBERON:0000397	78.42	gold quality
apex of heart	UBERON:0002098	76.95	gold quality
right adrenal gland	UBERON:0001233	75.34	gold quality
left adrenal gland cortex	UBERON:0035825	75.14	gold quality
left adrenal gland	UBERON:0001234	74.92	gold quality
mucosa of transverse colon	UBERON:0004991	74.63	gold quality
right adrenal gland cortex	UBERON:0035827	74.12	gold quality
adrenal gland	UBERON:0002369	74.01	gold quality
cortical plate	UBERON:0005343	73.48	gold quality
body of pancreas	UBERON:0001150	73.42	gold quality
right atrium auricular region	UBERON:0006631	73.02	gold quality
heart left ventricle	UBERON:0002084	72.61	gold quality
bone marrow	UBERON:0002371	72.40	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	72.34	gold quality
heart	UBERON:0000948	71.96	gold quality
pituitary gland	UBERON:0000007	71.90	gold quality
pancreas	UBERON:0001264	71.79	gold quality
stromal cell of endometrium	CL:0002255	71.66	gold quality
adenohypophysis	UBERON:0002196	71.50	gold quality
cortex of kidney	UBERON:0001225	71.43	gold quality
kidney	UBERON:0002113	71.24	gold quality
substantia nigra	UBERON:0002038	70.14	gold quality
tonsil	UBERON:0002372	70.09	gold quality
muscle tissue	UBERON:0002385	69.92	gold quality
right lobe of thyroid gland	UBERON:0001119	69.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.