FAM88D

Summary

FAM88D (family with sequence similarity 88 member D, HGNC:56160) is a long non-coding RNA gene on chromosome 9p12.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56160
Approved symbol	FAM88D
Name	family with sequence similarity 88 member D
Location	9p12
Locus type	RNA, long non-coding
Status	Approved
Entrez	554249
RNAcentral	URS00007E4C26 — lncRNA, 1424 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 2 (showing top): ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN, chr9p12

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 74 via entrez): RS1218960813 (9:39874284 A>C), RS1343284129 (9:39874157 A>G), RS1554678459 (9:39872124 G>GA), RS1554678460 (9:39872545 G>A), RS1554678461 (9:39873214 C>T), RS1554678464 (9:39873368 G>T), RS1554678466 (9:39873377 C>G), RS1554678467 (9:39873401 T>C), RS1554678469 (9:39873522 T>G), RS1554678470 (9:39873561 T>C), RS1554678471 (9:39873599 A>G), RS1554678472 (9:39873678 T>C), RS1554678474 (9:39873970 C>T), RS1554678478 (9:39873994 C>T), RS1554678481 (9:39874035 G>C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Smoke	decreases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.