FAM88E

Summary

FAM88E (family with sequence similarity 88 member E, HGNC:56161) is a long non-coding RNA gene on chromosome 9p11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56161
Approved symbol	FAM88E
Name	family with sequence similarity 88 member E
Location	9p11.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237357
Ensembl biotype	lncRNA
Entrez	103908605
RNAcentral	URS00007E4C08 — lncRNA, 522 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 45 — 45 lncRNA

ENST00000428895, ENST00000435586, ENST00000806170, ENST00000806171, ENST00000806172, ENST00000806173, ENST00000806174, ENST00000806175, ENST00000806176, ENST00000806177, ENST00000806178, ENST00000806179, ENST00000806180, ENST00000806181, ENST00000806182, ENST00000806183, ENST00000806184, ENST00000806185, ENST00000806186, ENST00000806187, ENST00000806188, ENST00000806189, ENST00000806190, ENST00000806191, ENST00000806192, ENST00000806193, ENST00000806194, ENST00000806195, ENST00000806196, ENST00000806197, ENST00000806198, ENST00000806199, ENST00000806200, ENST00000806201, ENST00000806202, ENST00000806203, ENST00000806204, ENST00000806205, ENST00000806206, ENST00000806207, ENST00000806208, ENST00000806209, ENST00000806210, ENST00000806211, ENST00000806212

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428895 — 3 exons

Exon	Start	End
ENSE00001709563	42568785	42568914
ENSE00004198999	42566993	42568059
ENSE00004199017	42569029	42569403

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 70.10.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	70.10	gold quality
lower esophagus mucosa	UBERON:0035834	68.72	gold quality
ventricular zone	UBERON:0003053	67.01	gold quality
ganglionic eminence	UBERON:0004023	66.24	gold quality
cortical plate	UBERON:0005343	66.03	gold quality
skin of leg	UBERON:0001511	64.95	gold quality
esophagus mucosa	UBERON:0002469	64.34	gold quality
zone of skin	UBERON:0000014	64.15	gold quality
right adrenal gland	UBERON:0001233	63.25	gold quality
left adrenal gland cortex	UBERON:0035825	63.03	gold quality
right adrenal gland cortex	UBERON:0035827	62.97	gold quality
skin of abdomen	UBERON:0001416	62.90	gold quality
left adrenal gland	UBERON:0001234	61.46	gold quality
right lung	UBERON:0002167	61.11	gold quality
adrenal gland	UBERON:0002369	61.06	gold quality
body of pancreas	UBERON:0001150	60.47	gold quality
adult mammalian kidney	UBERON:0000082	59.97	gold quality
vagina	UBERON:0000996	59.85	gold quality
pancreas	UBERON:0001264	59.54	gold quality
esophagus	UBERON:0001043	59.28	gold quality
pituitary gland	UBERON:0000007	58.41	gold quality
kidney	UBERON:0002113	58.33	gold quality
minor salivary gland	UBERON:0001830	58.26	gold quality
adenohypophysis	UBERON:0002196	58.23	gold quality
saliva-secreting gland	UBERON:0001044	57.86	gold quality
islet of Langerhans	UBERON:0000006	57.83	gold quality
tibial nerve	UBERON:0001323	57.35	gold quality
duodenum	UBERON:0002114	57.05	gold quality
cortex of kidney	UBERON:0001225	56.74	gold quality
apex of heart	UBERON:0002098	56.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.