FAM95C

Summary

FAM95C (family with sequence similarity 95 member C, HGNC:45272) is a long non-coding RNA gene on chromosome 9p13.1.

At a glance

• Clinical variants (ClinVar): 6 total

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45272
Approved symbol	FAM95C
Name	family with sequence similarity 95 member C
Location	9p13.1
Locus type	RNA, long non-coding
Status	Approved
Entrez	100289137
RNAcentral	URS000075ABDD — lncRNA, 2667 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

6 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000000570 (9:38544537 T>A,C,G), RS1001364347 (9:38543781 C>G,T), RS1003042499 (9:38542406 C>T), RS1003094895 (9:38542615 C>T), RS1003407140 (9:38546808 CG>C), RS1003427261 (9:38541438 G>T), RS1003664530 (9:38546597 GA>G), RS1003895693 (9:38544766 C>A), RS1005873587 (9:38542584 G>A,T), RS1006895804 (9:38542902 G>A), RS1007026686 (9:38543245 T>C), RS1007228148 (9:38541807 C>G,T), RS1007257693 (9:38547001 A>G,T), RS1009340621 (9:38545879 C>T), RS1010723970 (9:38541750 T>C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

7 total (human), top 7 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
aristolochic acid I	increases expression	1
triphenyl phosphate	affects expression	1
S-(1,2-dichlorovinyl)cysteine	affects response to substance, increases expression, affects cotreatment	1
2,3,5-trichloro-6-phenyl-(1,4)benzoquinone	decreases expression	1
Lipopolysaccharides	affects cotreatment, increases expression, affects response to substance	1
Thiram	decreases expression	1
Propofol	decreases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.