FBXO3-DT

Summary

FBXO3-DT (FBXO3 divergent transcript, HGNC:51147) is a long non-coding RNA gene on chromosome 11p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51147
Approved symbol	FBXO3-DT
Name	FBXO3 divergent transcript
Location	11p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254508
Ensembl biotype	lncRNA
Entrez	101928440
RNAcentral	URS000057EDD1 — lncRNA, 386 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 30 — 30 lncRNA

ENST00000527270, ENST00000528779, ENST00000530352, ENST00000533046, ENST00000534666, ENST00000718487, ENST00000718488, ENST00000718489, ENST00000718490, ENST00000754122, ENST00000754123, ENST00000754124, ENST00000754125, ENST00000754126, ENST00000754127, ENST00000754128, ENST00000754129, ENST00000754130, ENST00000754131, ENST00000754132, ENST00000755627, ENST00000755628, ENST00000755629, ENST00000755630, ENST00000755631, ENST00000755632, ENST00000755633, ENST00000755634, ENST00000755635, ENST00000850653

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527270 — 3 exons

Exon	Start	End
ENSE00004035245	33810945	33811178
ENSE00004104909	33809787	33810231
ENSE00004104911	33808495	33808620

Expression profiles

Bgee: expression breadth broad, 84 present calls, max score 92.89.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0931 / max 26.6140, expressed in 21 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
113692	0.0796	20
113691	0.0135	5

Top tissues by expression

84 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.89	gold quality
left testis	UBERON:0004533	82.85	gold quality
testis	UBERON:0000473	82.24	gold quality
right testis	UBERON:0004534	81.43	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.69	gold quality
skeletal muscle tissue	UBERON:0001134	66.60	gold quality
bone marrow	UBERON:0002371	64.42	gold quality
blood	UBERON:0000178	60.57	gold quality
monocyte	CL:0000576	58.85	gold quality
islet of Langerhans	UBERON:0000006	56.82	gold quality
muscle of leg	UBERON:0001383	55.24	gold quality
primary visual cortex	UBERON:0002436	54.49	gold quality
gastrocnemius	UBERON:0001388	53.04	gold quality
multicellular organism	UBERON:0000468	52.98	gold quality
right lobe of liver	UBERON:0001114	51.58	gold quality
liver	UBERON:0002107	51.16	gold quality
prefrontal cortex	UBERON:0000451	50.38	gold quality
adult mammalian kidney	UBERON:0000082	49.98	gold quality
kidney	UBERON:0002113	49.53	gold quality
heart left ventricle	UBERON:0002084	48.95	gold quality
body of pancreas	UBERON:0001150	48.88	gold quality
tibial artery	UBERON:0007610	47.90	gold quality
ascending aorta	UBERON:0001496	47.89	gold quality
skin of abdomen	UBERON:0001416	47.47	gold quality
right lobe of thyroid gland	UBERON:0001119	47.43	gold quality
left coronary artery	UBERON:0001626	47.41	gold quality
body of uterus	UBERON:0009853	47.01	gold quality
left adrenal gland cortex	UBERON:0035825	46.91	gold quality
stomach	UBERON:0000945	46.89	gold quality
body of stomach	UBERON:0001161	46.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.58

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.