FERRISR

Summary

FERRISR (ferroptosis inhibiting SLC7A11 regulator, HGNC:58367) is a long non-coding RNA gene on chromosome 1q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58367
Approved symbol	FERRISR
Name	ferroptosis inhibiting SLC7A11 regulator
Location	1q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	FERRIN
Ensembl gene	ENSG00000274265
Ensembl biotype	lncRNA
Entrez	143222015

Gene structure

Transcript identifiers

Ensembl transcripts: 123 — 123 lncRNA

ENST00000610119, ENST00000611769, ENST00000612135, ENST00000619653, ENST00000654174, ENST00000655610, ENST00000662742, ENST00000664903, ENST00000665384, ENST00000667654, ENST00000668239, ENST00000788353, ENST00000788354, ENST00000788355, ENST00000788356, ENST00000788357, ENST00000788358, ENST00000788359, ENST00000788360, ENST00000788361, ENST00000788362, ENST00000788363, ENST00000788364, ENST00000788365, ENST00000788366, ENST00000788367, ENST00000788368, ENST00000788369, ENST00000788370, ENST00000788371, ENST00000788372, ENST00000788373, ENST00000788374, ENST00000788375, ENST00000788376, ENST00000788377, ENST00000788378, ENST00000788379, ENST00000788380, ENST00000788381, ENST00000788382, ENST00000788383, ENST00000788384, ENST00000788385, ENST00000788386, ENST00000788387, ENST00000788388, ENST00000788389, ENST00000788390, ENST00000788391, ENST00000788392, ENST00000788393, ENST00000788394, ENST00000788395, ENST00000788396, ENST00000788397, ENST00000788398, ENST00000788399, ENST00000788400, ENST00000788401, ENST00000788402, ENST00000788403, ENST00000788404, ENST00000788405, ENST00000788406, ENST00000788407, ENST00000788408, ENST00000788409, ENST00000788410, ENST00000788411, ENST00000788412, ENST00000788413, ENST00000788414, ENST00000788415, ENST00000788416, ENST00000788417, ENST00000788418, ENST00000788419, ENST00000788420, ENST00000788421, ENST00000788422, ENST00000788423, ENST00000788424, ENST00000788425, ENST00000788426, ENST00000788427, ENST00000788428, ENST00000788429, ENST00000788430, ENST00000788431, ENST00000788432, ENST00000788433, ENST00000788434, ENST00000788435, ENST00000788436, ENST00000788437, ENST00000788438, ENST00000788439, ENST00000788440, ENST00000788441, ENST00000788442, ENST00000788443, ENST00000788444, ENST00000788445, ENST00000788446, ENST00000788447, ENST00000788448, ENST00000788449, ENST00000788450, ENST00000788451, ENST00000788452, ENST00000788453, ENST00000788454, ENST00000788455, ENST00000788456, ENST00000788457, ENST00000788458, ENST00000788459, ENST00000788460, ENST00000788461, ENST00000788462, ENST00000788463, ENST00000788464

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000610119 — 1 exons

Exon	Start	End
ENSE00003704660	149264252	149264816

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 97.37.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	97.37	gold quality
colonic epithelium	UBERON:0000397	96.86	gold quality
bone marrow cell	CL:0002092	95.56	gold quality
calcaneal tendon	UBERON:0003701	95.52	gold quality
gastrocnemius	UBERON:0001388	94.65	gold quality
right hemisphere of cerebellum	UBERON:0014890	94.58	gold quality
muscle of leg	UBERON:0001383	94.36	gold quality
cerebellar hemisphere	UBERON:0002245	93.76	gold quality
cerebellar cortex	UBERON:0002129	93.75	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	93.74	gold quality
cerebellum	UBERON:0002037	93.63	gold quality
hindlimb stylopod muscle	UBERON:0004252	92.96	gold quality
substantia nigra	UBERON:0002038	92.36	gold quality
sural nerve	UBERON:0015488	92.19	gold quality
skeletal muscle tissue	UBERON:0001134	91.70	gold quality
amygdala	UBERON:0001876	91.11	gold quality
bone marrow	UBERON:0002371	91.07	gold quality
temporal lobe	UBERON:0001871	91.05	gold quality
hypothalamus	UBERON:0001898	91.03	gold quality
heart left ventricle	UBERON:0002084	91.03	gold quality
tonsil	UBERON:0002372	91.01	gold quality
popliteal artery	UBERON:0002250	90.99	gold quality
tibial artery	UBERON:0007610	90.99	gold quality
Ammon’s horn	UBERON:0001954	90.87	gold quality
apex of heart	UBERON:0002098	90.41	gold quality
heart	UBERON:0000948	90.29	gold quality
right uterine tube	UBERON:0001302	89.90	gold quality
mucosa of stomach	UBERON:0001199	89.64	gold quality
muscle tissue	UBERON:0002385	89.43	gold quality
right atrium auricular region	UBERON:0006631	89.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.