FGF13-AS1

Summary

FGF13-AS1 (FGF13 antisense RNA 1, HGNC:44264) is a long non-coding RNA gene on chromosome Xq26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44264
Approved symbol	FGF13-AS1
Name	FGF13 antisense RNA 1
Location	Xq26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226031
Ensembl biotype	lncRNA
OMIM	301087
Entrez	100129662
RNAcentral	URS000075E212 — lncRNA, 849 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000438238, ENST00000446383, ENST00000743666

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438238 — 3 exons

Exon	Start	End
ENSE00001625145	138714724	138714809
ENSE00001691832	138712107	138712142
ENSE00001719930	138715891	138716617

Expression profiles

Bgee: expression breadth ubiquitous, 148 present calls, max score 96.23.

Top tissues by expression

238 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.23	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.85	gold quality
colonic epithelium	UBERON:0000397	79.70	gold quality
popliteal artery	UBERON:0002250	76.90	gold quality
tibial artery	UBERON:0007610	76.89	gold quality
right coronary artery	UBERON:0001625	75.23	gold quality
aorta	UBERON:0000947	75.02	gold quality
descending thoracic aorta	UBERON:0002345	74.25	gold quality
left coronary artery	UBERON:0001626	73.19	gold quality
thoracic aorta	UBERON:0001515	72.99	gold quality
ascending aorta	UBERON:0001496	72.77	gold quality
coronary artery	UBERON:0001621	71.57	gold quality
bone marrow cell	CL:0002092	68.19	silver quality
calcaneal tendon	UBERON:0003701	66.22	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.09	gold quality
ventricular zone	UBERON:0003053	65.61	gold quality
mucosa of stomach	UBERON:0001199	65.23	gold quality
ganglionic eminence	UBERON:0004023	64.45	gold quality
cortical plate	UBERON:0005343	64.41	gold quality
adipose tissue	UBERON:0001013	64.03	gold quality
omental fat pad	UBERON:0010414	63.28	gold quality
peritoneum	UBERON:0002358	63.21	gold quality
adipose tissue of abdominal region	UBERON:0007808	62.54	gold quality
lower esophagus muscularis layer	UBERON:0035833	62.35	gold quality
lower esophagus	UBERON:0013473	62.33	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	62.07	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.96	gold quality
left lobe of thyroid gland	UBERON:0001120	61.01	gold quality
smooth muscle tissue	UBERON:0001135	60.87	gold quality
thyroid gland	UBERON:0002046	60.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.27

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Results reveal for the first time that FGF13-AS1 functions as a tumor suppressor by inhibiting glycolysis and stemness properties of breast cancer cells, and the FGF13-AS1/IGF2BPs/Myc feedback loop. (PMID:30771425)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.