FGF14-IT1

Summary

FGF14-IT1 (FGF14 intronic transcript 1, HGNC:42774) is a long non-coding RNA gene on chromosome 13q33.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42774
Approved symbol	FGF14-IT1
Name	FGF14 intronic transcript 1
Location	13q33.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243319
Ensembl biotype	lncRNA
Entrez	283480
RNAcentral	URS000075D011 — lncRNA, 2130 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000437115, ENST00000607251

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000437115 — 4 exons

Exon	Start	End
ENSE00001695993	102367257	102367399
ENSE00001769298	102366445	102366613
ENSE00001797088	102292687	102294040
ENSE00003700612	102354110	102354222

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 98.84.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3033 / max 22.1032, expressed in 157 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
138097	0.2994	156
138095	0.0038	3

Top tissues by expression

201 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	98.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.94	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.85	gold quality
left testis	UBERON:0004533	71.07	gold quality
right testis	UBERON:0004534	69.95	gold quality
testis	UBERON:0000473	69.90	gold quality
calcaneal tendon	UBERON:0003701	65.00	gold quality
colonic epithelium	UBERON:0000397	61.34	silver quality
corpus callosum	UBERON:0002336	60.38	gold quality
cortical plate	UBERON:0005343	58.54	silver quality
ventricular zone	UBERON:0003053	58.00	silver quality
cerebellar vermis	UBERON:0004720	57.89	gold quality
tibialis anterior	UBERON:0001385	57.27	silver quality
pancreatic ductal cell	CL:0002079	57.16	silver quality
right lobe of liver	UBERON:0001114	56.42	gold quality
cerebellar cortex	UBERON:0002129	56.31	gold quality
cerebellum	UBERON:0002037	56.01	gold quality
cerebellar hemisphere	UBERON:0002245	55.88	gold quality
tendon	UBERON:0000043	55.85	gold quality
adrenal tissue	UBERON:0018303	55.02	gold quality
right hemisphere of cerebellum	UBERON:0014890	54.96	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
epithelial cell of pancreas	CL:0000083	54.31	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
skin of hip	UBERON:0001554	53.04	silver quality
deltoid	UBERON:0001476	51.95	gold quality
right uterine tube	UBERON:0001302	51.83	gold quality
sural nerve	UBERON:0015488	51.80	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.88

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.