FGL1-AS1

Summary

FGL1-AS1 (FGL1 antisense RNA 1, HGNC:58257) is a long non-coding RNA gene on chromosome 8p22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58257
Approved symbol	FGL1-AS1
Name	FGL1 antisense RNA 1
Location	8p22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254054
Ensembl biotype	lncRNA
Entrez	139355248
RNAcentral	URS0000EEBECF — lncRNA, 1317 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000519038, ENST00000667767, ENST00000846079

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000519038 — 3 exons

Exon	Start	End
ENSE00002099133	17907193	17907394
ENSE00002129514	17907556	17908011
ENSE00002138493	17905197	17905855

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 81.16.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.16	silver quality
endometrium	UBERON:0001295	72.63	gold quality
bone marrow cell	CL:0002092	68.10	silver quality
monocyte	CL:0000576	67.86	gold quality
placenta	UBERON:0001987	62.62	gold quality
islet of Langerhans	UBERON:0000006	62.42	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.82	gold quality
granulocyte	CL:0000094	60.72	gold quality
prostate gland	UBERON:0002367	59.74	gold quality
liver	UBERON:0002107	58.93	gold quality
ganglionic eminence	UBERON:0004023	58.87	gold quality
left testis	UBERON:0004533	58.15	gold quality
right lobe of liver	UBERON:0001114	58.04	gold quality
testis	UBERON:0000473	57.82	gold quality
cortical plate	UBERON:0005343	57.75	gold quality
bone marrow	UBERON:0002371	57.35	silver quality
right testis	UBERON:0004534	57.14	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	56.96	gold quality
substantia nigra	UBERON:0002038	55.94	gold quality
prefrontal cortex	UBERON:0000451	55.92	gold quality
blood	UBERON:0000178	55.83	gold quality
pancreas	UBERON:0001264	55.55	gold quality
right lung	UBERON:0002167	55.07	gold quality
amygdala	UBERON:0001876	54.25	gold quality
putamen	UBERON:0001874	53.81	gold quality
Ammon’s horn	UBERON:0001954	53.07	gold quality
corpus callosum	UBERON:0002336	52.33	gold quality
caudate nucleus	UBERON:0001873	52.25	gold quality
anterior cingulate cortex	UBERON:0009835	52.11	gold quality
right adrenal gland	UBERON:0001233	52.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.