FLNB-AS1
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Summary
FLNB-AS1 (FLNB antisense RNA 1, HGNC:40239) is a long non-coding RNA gene on chromosome 3p14.3.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:40239 |
| Approved symbol | FLNB-AS1 |
| Name | FLNB antisense RNA 1 |
| Location | 3p14.3 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000244161 |
| Ensembl biotype | lncRNA |
| Entrez | 105377105 |
| RNAcentral | URS0000A76CB1 — lncRNA, 3708 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 2 — 2 lncRNA
ENST00000472922, ENST00000488720
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000472922 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001906234 | 58165084 | 58165314 |
| ENSE00001931049 | 58163973 | 58164312 |
Expression profiles
Bgee: expression breadth ubiquitous, 153 present calls, max score 72.49.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0115 / max 6.8718, expressed in 3 samples.
FANTOM5 promoters (1 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 42672 | 0.0115 | 3 |
Top tissues by expression
240 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| transverse colon | UBERON:0001157 | 72.49 | gold quality |
| mucosa of stomach | UBERON:0001199 | 71.28 | gold quality |
| body of uterus | UBERON:0009853 | 71.12 | gold quality |
| popliteal artery | UBERON:0002250 | 70.76 | gold quality |
| tibial artery | UBERON:0007610 | 70.70 | gold quality |
| body of pancreas | UBERON:0001150 | 70.20 | gold quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 70.05 | gold quality |
| right coronary artery | UBERON:0001625 | 69.85 | gold quality |
| aorta | UBERON:0000947 | 69.07 | gold quality |
| tibial nerve | UBERON:0001323 | 69.05 | gold quality |
| colonic epithelium | UBERON:0000397 | 68.87 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 68.02 | gold quality |
| lower esophagus | UBERON:0013473 | 68.00 | gold quality |
| left coronary artery | UBERON:0001626 | 67.95 | gold quality |
| colon | UBERON:0001155 | 67.63 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 67.57 | gold quality |
| small intestine Peyer’s patch | UBERON:0003454 | 67.48 | gold quality |
| left uterine tube | UBERON:0001303 | 67.41 | gold quality |
| skin of abdomen | UBERON:0001416 | 67.33 | gold quality |
| ascending aorta | UBERON:0001496 | 67.29 | gold quality |
| thoracic aorta | UBERON:0001515 | 67.22 | gold quality |
| large intestine | UBERON:0000059 | 67.04 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 67.01 | gold quality |
| mucosa of transverse colon | UBERON:0004991 | 66.91 | gold quality |
| skin of leg | UBERON:0001511 | 66.85 | gold quality |
| body of stomach | UBERON:0001161 | 66.69 | gold quality |
| coronary artery | UBERON:0001621 | 66.60 | gold quality |
| intestine | UBERON:0000160 | 66.49 | gold quality |
| right lobe of thyroid gland | UBERON:0001119 | 66.18 | gold quality |
| left lobe of thyroid gland | UBERON:0001120 | 66.03 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 2.66 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): spondylocarpotarsal synostosis syndrome