FLNC-AS1
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Summary
FLNC-AS1 (FLNC antisense RNA 1, HGNC:53474) is a long non-coding RNA gene on chromosome 7q32.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:53474 |
| Approved symbol | FLNC-AS1 |
| Name | FLNC antisense RNA 1 |
| Location | 7q32.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000242902 |
| Ensembl biotype | lncRNA |
| Entrez | 110806300 |
| RNAcentral | URS00002149EF — lncRNA, 559 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000469965
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000469965 — 4 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001821550 | 128862525 | 128862626 |
| ENSE00001842708 | 128853285 | 128853397 |
| ENSE00001854164 | 128850162 | 128850405 |
| ENSE00001908690 | 128851401 | 128851500 |
Expression profiles
Bgee: expression breadth ubiquitous, 114 present calls, max score 86.06.
Top tissues by expression
114 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| hindlimb stylopod muscle | UBERON:0004252 | 86.06 | gold quality |
| apex of heart | UBERON:0002098 | 83.55 | gold quality |
| muscle of leg | UBERON:0001383 | 79.32 | gold quality |
| heart left ventricle | UBERON:0002084 | 79.01 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 78.36 | gold quality |
| gastrocnemius | UBERON:0001388 | 77.33 | gold quality |
| right atrium auricular region | UBERON:0006631 | 75.68 | gold quality |
| heart | UBERON:0000948 | 74.45 | gold quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 65.39 | gold quality |
| ventricular zone | UBERON:0003053 | 65.12 | gold quality |
| colonic epithelium | UBERON:0000397 | 65.06 | silver quality |
| stromal cell of endometrium | CL:0002255 | 64.32 | gold quality |
| gall bladder | UBERON:0002110 | 63.71 | gold quality |
| urinary bladder | UBERON:0001255 | 63.33 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 62.30 | gold quality |
| popliteal artery | UBERON:0002250 | 62.25 | gold quality |
| lower esophagus | UBERON:0013473 | 62.25 | gold quality |
| tibial artery | UBERON:0007610 | 62.19 | gold quality |
| mucosa of stomach | UBERON:0001199 | 61.87 | gold quality |
| colon | UBERON:0001155 | 61.68 | gold quality |
| cerebellum | UBERON:0002037 | 61.28 | gold quality |
| cerebellar cortex | UBERON:0002129 | 61.23 | gold quality |
| cerebellar hemisphere | UBERON:0002245 | 61.18 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 60.87 | gold quality |
| ascending aorta | UBERON:0001496 | 60.64 | gold quality |
| intestine | UBERON:0000160 | 60.61 | gold quality |
| thoracic aorta | UBERON:0001515 | 59.73 | gold quality |
| vermiform appendix | UBERON:0001154 | 59.53 | gold quality |
| myometrium | UBERON:0001296 | 59.50 | gold quality |
| fundus of stomach | UBERON:0001160 | 59.38 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.23 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): cardiomyopathy, familial restrictive, 5, cerebellar ataxia, distal myopathy with posterior leg and anterior hand involvement, familial dilated cardiomyopathy, familial hypertrophic cardiomyopathy, familial long QT syndrome, hypertrophic cardiomyopathy 26, myofibrillar myopathy, myofibrillar myopathy 5, restrictive cardiomyopathy, spastic ataxia, Wolff-Parkinson-White syndrome