FMNL1-AS1

Summary

FMNL1-AS1 (FMNL1 antisense RNA 1, HGNC:55717) is a long non-coding RNA gene on chromosome 17q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55717
Approved symbol	FMNL1-AS1
Name	FMNL1 antisense RNA 1
Location	17q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233175
Ensembl biotype	lncRNA
Entrez	107985040
RNAcentral	URS00026A23D9 — lncRNA, 2049 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000393507, ENST00000587534, ENST00000743963

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000393507 — 3 exons

Exon	Start	End
ENSE00004082860	45240303	45240604
ENSE00004082861	45241111	45241495
ENSE00004082863	45241856	45241900

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 98.17.

Top tissues by expression

136 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	98.17	gold quality
right hemisphere of cerebellum	UBERON:0014890	90.26	gold quality
cerebellar hemisphere	UBERON:0002245	90.16	gold quality
cerebellar cortex	UBERON:0002129	90.05	gold quality
cerebellum	UBERON:0002037	89.99	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.90	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.55	gold quality
bone marrow cell	CL:0002092	88.24	gold quality
bone marrow	UBERON:0002371	83.29	gold quality
pituitary gland	UBERON:0000007	82.18	gold quality
cerebellar vermis	UBERON:0004720	81.90	gold quality
adenohypophysis	UBERON:0002196	81.63	gold quality
primary visual cortex	UBERON:0002436	80.21	gold quality
prefrontal cortex	UBERON:0000451	79.80	gold quality
sural nerve	UBERON:0015488	79.44	gold quality
frontal cortex	UBERON:0001870	79.20	gold quality
right frontal lobe	UBERON:0002810	78.75	gold quality
Brodmann (1909) area 9	UBERON:0013540	78.44	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	78.40	gold quality
superior frontal gyrus	UBERON:0002661	78.39	gold quality
brain	UBERON:0000955	78.32	gold quality
cerebral cortex	UBERON:0000956	77.97	gold quality
anterior cingulate cortex	UBERON:0009835	77.93	gold quality
blood	UBERON:0000178	77.38	gold quality
cortical plate	UBERON:0005343	77.09	gold quality
hypothalamus	UBERON:0001898	76.99	gold quality
nucleus accumbens	UBERON:0001882	76.09	gold quality
granulocyte	CL:0000094	75.54	gold quality
colonic epithelium	UBERON:0000397	75.20	gold quality
monocyte	CL:0000576	74.92	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.