FMNL1-DT

Summary

FMNL1-DT (FMNL1 divergent transcript, HGNC:55311) is a long non-coding RNA gene on chromosome 17q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55311
Approved symbol	FMNL1-DT
Name	FMNL1 divergent transcript
Location	17q21.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTD-2020K17.1
Ensembl gene	ENSG00000267121
Ensembl biotype	lncRNA
Entrez	339192
RNAcentral	URS00001418AD — lncRNA, 844 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000585471, ENST00000586376, ENST00000590495, ENST00000590522, ENST00000591365, ENST00000670229, ENST00000706644, ENST00000827002, ENST00000827003, ENST00000827004, ENST00000827005, ENST00000827006, ENST00000827007, ENST00000827008, ENST00000827009

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000585471 — 3 exons

Exon	Start	End
ENSE00002944332	45220268	45220454
ENSE00004238459	45218256	45219174
ENSE00004238463	45221349	45221552

Expression profiles

Bgee: expression breadth ubiquitous, 136 present calls, max score 94.38.

FANTOM5 (CAGE): breadth broad, TPM avg 6.0989 / max 221.1353, expressed in 679 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
166513	3.0746	397
166515	2.7075	514
166514	0.2194	109
166512	0.0974	41

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	94.38	gold quality
granulocyte	CL:0000094	93.86	gold quality
blood	UBERON:0000178	93.15	gold quality
monocyte	CL:0000576	92.37	gold quality
leukocyte	CL:0000738	91.60	gold quality
spleen	UBERON:0002106	89.54	gold quality
vermiform appendix	UBERON:0001154	89.53	gold quality
lymph node	UBERON:0000029	89.17	gold quality
bone marrow cell	CL:0002092	84.53	gold quality
bone marrow	UBERON:0002371	84.21	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.87	gold quality
gall bladder	UBERON:0002110	80.66	gold quality
small intestine Peyer’s patch	UBERON:0003454	80.61	gold quality
apex of heart	UBERON:0002098	80.29	gold quality
mucosa of stomach	UBERON:0001199	79.80	gold quality
endocervix	UBERON:0000458	79.70	gold quality
small intestine	UBERON:0002108	79.57	gold quality
upper lobe of left lung	UBERON:0008952	79.48	gold quality
primary visual cortex	UBERON:0002436	79.16	gold quality
tonsil	UBERON:0002372	79.02	gold quality
right frontal lobe	UBERON:0002810	78.34	gold quality
mucosa of transverse colon	UBERON:0004991	77.79	gold quality
right lung	UBERON:0002167	77.06	gold quality
ectocervix	UBERON:0012249	76.78	gold quality
omental fat pad	UBERON:0010414	76.71	gold quality
right coronary artery	UBERON:0001625	76.68	gold quality
vagina	UBERON:0000996	76.67	gold quality
lung	UBERON:0002048	76.53	gold quality
uterine cervix	UBERON:0000002	76.37	gold quality
superior frontal gyrus	UBERON:0002661	76.28	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	4.75
E-ANND-3	yes	4.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.