FMR1-IT1

Summary

FMR1-IT1 (FMR1 intronic transcript 1, HGNC:41333) is a long non-coding RNA gene on chromosome Xq27.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41333
Approved symbol	FMR1-IT1
Name	FMR1 intronic transcript 1
Location	Xq27.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236337
Ensembl biotype	lncRNA
Entrez	106478973
RNAcentral	URS00004D6662 — lncRNA, 343 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000441414

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000441414 — 2 exons

Exon	Start	End
ENSE00001596476	147947480	147947583
ENSE00001641677	147946941	147947179

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 89.51.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	89.51	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.98	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.90	gold quality
endometrium	UBERON:0001295	77.70	gold quality
bone marrow	UBERON:0002371	75.37	gold quality
monocyte	CL:0000576	75.09	gold quality
leukocyte	CL:0000738	74.51	gold quality
left ovary	UBERON:0002119	72.21	gold quality
ovary	UBERON:0000992	71.21	gold quality
skin of abdomen	UBERON:0001416	71.00	gold quality
granulocyte	CL:0000094	70.75	gold quality
thoracic mammary gland	UBERON:0005200	70.56	gold quality
adrenal tissue	UBERON:0018303	70.52	gold quality
zone of skin	UBERON:0000014	70.46	gold quality
right ovary	UBERON:0002118	70.26	gold quality
skin of leg	UBERON:0001511	70.12	gold quality
thyroid gland	UBERON:0002046	70.07	gold quality
rectum	UBERON:0001052	70.04	gold quality
calcaneal tendon	UBERON:0003701	69.97	gold quality
left lobe of thyroid gland	UBERON:0001120	69.46	gold quality
subcutaneous adipose tissue	UBERON:0002190	69.42	gold quality
tibial nerve	UBERON:0001323	69.38	gold quality
urinary bladder	UBERON:0001255	69.33	gold quality
popliteal artery	UBERON:0002250	69.29	gold quality
right lobe of thyroid gland	UBERON:0001119	69.28	gold quality
tibial artery	UBERON:0007610	69.28	gold quality
upper lobe of left lung	UBERON:0008952	69.21	gold quality
myometrium	UBERON:0001296	69.07	gold quality
ectocervix	UBERON:0012249	69.04	gold quality
ganglionic eminence	UBERON:0004023	68.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.59

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.