FOS-AS1

Summary

FOS-AS1 (FOS antisense RNA 1, HGNC:58290) is a long non-coding RNA gene on chromosome 14q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58290
Approved symbol	FOS-AS1
Name	FOS antisense RNA 1
Location	14q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258740
Ensembl biotype	lncRNA
Entrez	139432807
RNAcentral	URS0002A50E49 — lncRNA, 1048 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000553510, ENST00000789955, ENST00000789956, ENST00000789957, ENST00000789958, ENST00000789959, ENST00000789960, ENST00000789961

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553510 — 3 exons

Exon	Start	End
ENSE00004169738	75269180	75269295
ENSE00004169741	75238616	75239189
ENSE00004169751	75278031	75278388

Expression profiles

Bgee: expression breadth broad, 68 present calls, max score 77.01.

Top tissues by expression

75 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	77.01	gold quality
cerebellar vermis	UBERON:0004720	71.43	gold quality
bone marrow	UBERON:0002371	64.73	silver quality
spleen	UBERON:0002106	62.96	silver quality
liver	UBERON:0002107	61.47	silver quality
skeletal muscle tissue	UBERON:0001134	59.89	silver quality
thymus	UBERON:0002370	59.53	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	56.29	gold quality
ectocervix	UBERON:0012249	55.69	gold quality
placenta	UBERON:0001987	53.39	gold quality
kidney	UBERON:0002113	52.97	gold quality
uterine cervix	UBERON:0000002	52.52	gold quality
cortex of kidney	UBERON:0001225	52.49	gold quality
islet of Langerhans	UBERON:0000006	52.23	gold quality
monocyte	CL:0000576	51.46	silver quality
blood	UBERON:0000178	51.21	silver quality
anterior cingulate cortex	UBERON:0009835	50.92	silver quality
skin of abdomen	UBERON:0001416	50.89	gold quality
prefrontal cortex	UBERON:0000451	50.72	gold quality
substantia nigra	UBERON:0002038	50.70	gold quality
calcaneal tendon	UBERON:0003701	50.35	silver quality
cerebellar cortex	UBERON:0002129	50.27	silver quality
adult mammalian kidney	UBERON:0000082	49.80	gold quality
zone of skin	UBERON:0000014	49.57	gold quality
subcutaneous adipose tissue	UBERON:0002190	49.50	silver quality
pancreas	UBERON:0001264	49.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	48.96	gold quality
skin of leg	UBERON:0001511	48.25	gold quality
vagina	UBERON:0000996	47.83	gold quality
muscle of leg	UBERON:0001383	47.28	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	29.30
E-ANND-3	no	0.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.