FOSL2-AS1

Summary

FOSL2-AS1 (FOSL2 antisense RNA 1, HGNC:55784) is a long non-coding RNA gene on chromosome 2p23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55784
Approved symbol	FOSL2-AS1
Name	FOSL2 antisense RNA 1
Location	2p23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229951
Ensembl biotype	lncRNA
Entrez	403150
RNAcentral	URS0000094EC2 — lncRNA, 2850 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000427929, ENST00000445878, ENST00000688938, ENST00000752534

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427929 — 2 exons

Exon	Start	End
ENSE00001598473	28394548	28394672
ENSE00001680893	28384409	28387133

Expression profiles

Bgee: expression breadth ubiquitous, 145 present calls, max score 83.55.

Top tissues by expression

228 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.55	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.05	gold quality
amniotic fluid	UBERON:0000173	69.68	gold quality
myocardium	UBERON:0002349	68.75	gold quality
tendon of biceps brachii	UBERON:0008188	66.35	silver quality
bone marrow cell	CL:0002092	64.95	silver quality
lower lobe of lung	UBERON:0008949	63.49	silver quality
left adrenal gland cortex	UBERON:0035825	63.36	gold quality
left adrenal gland	UBERON:0001234	63.02	gold quality
right adrenal gland	UBERON:0001233	62.08	gold quality
vena cava	UBERON:0004087	61.39	gold quality
adrenal cortex	UBERON:0001235	61.15	gold quality
adrenal gland	UBERON:0002369	61.14	gold quality
stromal cell of endometrium	CL:0002255	60.43	gold quality
right adrenal gland cortex	UBERON:0035827	58.95	gold quality
lower esophagus mucosa	UBERON:0035834	58.41	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.99	gold quality
islet of Langerhans	UBERON:0000006	57.91	gold quality
gastrocnemius	UBERON:0001388	57.66	gold quality
muscle of leg	UBERON:0001383	57.39	gold quality
muscle layer of sigmoid colon	UBERON:0035805	57.31	gold quality
endothelial cell	CL:0000115	57.28	gold quality
sural nerve	UBERON:0015488	57.21	silver quality
hindlimb stylopod muscle	UBERON:0004252	56.84	gold quality
pancreas	UBERON:0001264	56.55	gold quality
lower esophagus	UBERON:0013473	56.45	gold quality
lower esophagus muscularis layer	UBERON:0035833	56.44	gold quality
popliteal artery	UBERON:0002250	56.01	gold quality
body of pancreas	UBERON:0001150	55.97	gold quality
tibial artery	UBERON:0007610	55.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.67

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.