FOXG1-AS1

Summary

FOXG1-AS1 (FOXG1 antisense RNA 1, HGNC:50663) is a long non-coding RNA gene on chromosome 14q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50663
Approved symbol	FOXG1-AS1
Name	FOXG1 antisense RNA 1
Location	14q12
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.361, FOXG1-AS
Ensembl gene	ENSG00000257126
Ensembl biotype	lncRNA
Entrez	103695363
RNAcentral	URS00007E450A — lncRNA, 905 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000546560, ENST00000549487, ENST00000551395, ENST00000654854, ENST00000658593, ENST00000743607, ENST00000743608, ENST00000743609, ENST00000743610, ENST00000743611, ENST00000743612, ENST00000743613, ENST00000743614, ENST00000743615, ENST00000743616, ENST00000743617, ENST00000743618, ENST00000743619, ENST00000743620, ENST00000743621, ENST00000743622, ENST00000743623

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546560 — 5 exons

Exon	Start	End
ENSE00002350628	28738727	28738844
ENSE00002371266	28765160	28765263
ENSE00002375686	28729510	28729556
ENSE00002378610	28762332	28762474
ENSE00002409146	28741834	28741959

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 82.89.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1011 / max 8.0262, expressed in 54 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
142698	0.0511	39
142699	0.0500	40

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ganglionic eminence	UBERON:0004023	82.89	gold quality
ventricular zone	UBERON:0003053	82.12	gold quality
cortical plate	UBERON:0005343	79.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.46	gold quality
caudate nucleus	UBERON:0001873	69.39	gold quality
putamen	UBERON:0001874	68.81	gold quality
nucleus accumbens	UBERON:0001882	68.75	gold quality
prefrontal cortex	UBERON:0000451	67.87	gold quality
anterior cingulate cortex	UBERON:0009835	67.86	gold quality
frontal cortex	UBERON:0001870	67.55	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	67.45	gold quality
cerebral cortex	UBERON:0000956	67.37	gold quality
right frontal lobe	UBERON:0002810	67.19	gold quality
superior frontal gyrus	UBERON:0002661	66.94	gold quality
temporal lobe	UBERON:0001871	66.67	gold quality
amygdala	UBERON:0001876	66.57	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.34	gold quality
primary visual cortex	UBERON:0002436	64.64	gold quality
Ammon’s horn	UBERON:0001954	64.61	gold quality
corpus callosum	UBERON:0002336	64.38	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.15	gold quality
brain	UBERON:0000955	63.68	gold quality
muscle tissue	UBERON:0002385	62.10	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.77	gold quality
calcaneal tendon	UBERON:0003701	58.63	gold quality
islet of Langerhans	UBERON:0000006	55.64	gold quality
smooth muscle tissue	UBERON:0001135	55.28	gold quality
stromal cell of endometrium	CL:0002255	55.18	silver quality
blood	UBERON:0000178	54.61	gold quality
gall bladder	UBERON:0002110	54.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.