FREM2-AS1

Summary

FREM2-AS1 (FREM2 antisense RNA 1, HGNC:39964) is a long non-coding RNA gene on chromosome 13q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39964
Approved symbol	FREM2-AS1
Name	FREM2 antisense RNA 1
Location	13q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225350
Ensembl biotype	lncRNA
Entrez	100874073
RNAcentral	URS0000BC4428 — lncRNA, 600 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000448887

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000448887 — 2 exons

Exon	Start	End
ENSE00001640012	38821798	38822102
ENSE00001754492	38827411	38827570

Expression profiles

Bgee: expression breadth broad, 59 present calls, max score 81.72.

Top tissues by expression

59 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
body of pancreas	UBERON:0001150	81.72	gold quality
pancreas	UBERON:0001264	79.17	gold quality
adrenal tissue	UBERON:0018303	78.14	gold quality
skeletal muscle tissue	UBERON:0001134	64.89	gold quality
islet of Langerhans	UBERON:0000006	63.47	gold quality
muscle of leg	UBERON:0001383	60.97	gold quality
prefrontal cortex	UBERON:0000451	60.02	gold quality
gastrocnemius	UBERON:0001388	58.63	gold quality
multicellular organism	UBERON:0000468	56.35	gold quality
placenta	UBERON:0001987	55.98	gold quality
liver	UBERON:0002107	55.68	silver quality
hindlimb stylopod muscle	UBERON:0004252	54.97	gold quality
ovary	UBERON:0000992	54.58	gold quality
kidney	UBERON:0002113	53.75	gold quality
blood	UBERON:0000178	53.20	gold quality
ascending aorta	UBERON:0001496	52.30	gold quality
adult mammalian kidney	UBERON:0000082	52.06	gold quality
heart	UBERON:0000948	51.96	gold quality
lung	UBERON:0002048	50.50	gold quality
stomach	UBERON:0000945	49.39	gold quality
right lobe of liver	UBERON:0001114	49.33	silver quality
heart left ventricle	UBERON:0002084	48.66	gold quality
tibial artery	UBERON:0007610	48.55	gold quality
right adrenal gland	UBERON:0001233	47.09	gold quality
cortex of kidney	UBERON:0001225	46.94	gold quality
urinary bladder	UBERON:0001255	46.55	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	45.30	gold quality
endometrium	UBERON:0001295	45.24	silver quality
intestine	UBERON:0000160	44.65	silver quality
body of stomach	UBERON:0001161	44.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.