FRG1-DT

Summary

FRG1-DT (FRG1 divergent transcript, HGNC:51590) is a long non-coding RNA gene on chromosome 4q35.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51590
Approved symbol	FRG1-DT
Name	FRG1 divergent transcript
Location	4q35.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245685
Ensembl biotype	lncRNA
Entrez	728339
RNAcentral	URS0000BC453C — lncRNA, 2561 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 44 — 44 lncRNA

ENST00000501825, ENST00000506276, ENST00000508156, ENST00000511785, ENST00000656003, ENST00000657714, ENST00000660244, ENST00000661788, ENST00000688111, ENST00000691614, ENST00000691992, ENST00000701895, ENST00000847208, ENST00000847209, ENST00000847210, ENST00000847211, ENST00000847212, ENST00000847213, ENST00000847214, ENST00000847215, ENST00000847216, ENST00000847217, ENST00000847218, ENST00000847219, ENST00000847220, ENST00000847221, ENST00000847222, ENST00000847223, ENST00000847224, ENST00000847225, ENST00000847226, ENST00000847227, ENST00000847228, ENST00000847229, ENST00000847230, ENST00000847231, ENST00000847232, ENST00000847233, ENST00000847234, ENST00000847235, ENST00000847236, ENST00000847237, ENST00000847238, ENST00000847239

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501825 — 3 exons

Exon	Start	End
ENSE00001959289	189864262	189864786
ENSE00001977901	189939659	189939837
ENSE00001989730	189937197	189937333

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 84.02.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6223 / max 54.2742, expressed in 353 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
203466	0.6223	353

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.02	gold quality
corpus callosum	UBERON:0002336	80.73	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.61	gold quality
subcutaneous adipose tissue	UBERON:0002190	80.46	gold quality
left testis	UBERON:0004533	77.55	gold quality
right testis	UBERON:0004534	77.45	gold quality
testis	UBERON:0000473	77.27	gold quality
calcaneal tendon	UBERON:0003701	76.70	gold quality
sural nerve	UBERON:0015488	75.88	gold quality
adenohypophysis	UBERON:0002196	75.58	gold quality
adipose tissue	UBERON:0001013	75.15	gold quality
pituitary gland	UBERON:0000007	73.77	gold quality
thoracic mammary gland	UBERON:0005200	72.05	gold quality
adrenal tissue	UBERON:0018303	71.19	gold quality
cortical plate	UBERON:0005343	69.99	gold quality
omental fat pad	UBERON:0010414	68.69	gold quality
bone marrow cell	CL:0002092	68.31	silver quality
right ovary	UBERON:0002118	68.15	gold quality
ovary	UBERON:0000992	67.89	gold quality
left ovary	UBERON:0002119	67.81	gold quality
endometrium	UBERON:0001295	67.71	gold quality
right lobe of thyroid gland	UBERON:0001119	67.42	gold quality
colonic epithelium	UBERON:0000397	66.98	silver quality
right hemisphere of cerebellum	UBERON:0014890	66.71	gold quality
right uterine tube	UBERON:0001302	66.65	gold quality
ganglionic eminence	UBERON:0004023	66.44	gold quality
tibial nerve	UBERON:0001323	66.34	gold quality
cortex of kidney	UBERON:0001225	66.16	gold quality
kidney	UBERON:0002113	66.08	gold quality
cerebellum	UBERON:0002037	66.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.