FRMD4A-AS2

Summary

FRMD4A-AS2 (FRMD4A antisense RNA 2, HGNC:58179) is a long non-coding RNA gene on chromosome 10p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58179
Approved symbol	FRMD4A-AS2
Name	FRMD4A antisense RNA 2
Location	10p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229751
Ensembl biotype	lncRNA
Entrez	105376425
RNAcentral	URS00002ECC28 — lncRNA, 570 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000446193

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000446193 — 3 exons

Exon	Start	End
ENSE00001703051	14007187	14007526
ENSE00001778408	13991815	13991992
ENSE00001785855	14003526	14003577

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 94.02.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.02	silver quality
corpus callosum	UBERON:0002336	74.66	gold quality
colonic epithelium	UBERON:0000397	72.02	gold quality
cortical plate	UBERON:0005343	69.69	gold quality
ganglionic eminence	UBERON:0004023	63.69	gold quality
superior frontal gyrus	UBERON:0002661	63.55	gold quality
skeletal muscle tissue	UBERON:0001134	62.15	silver quality
adrenal tissue	UBERON:0018303	59.59	gold quality
sural nerve	UBERON:0015488	59.32	silver quality
endometrium	UBERON:0001295	57.44	gold quality
calcaneal tendon	UBERON:0003701	57.38	gold quality
urinary bladder	UBERON:0001255	57.11	gold quality
lymph node	UBERON:0000029	56.90	gold quality
monocyte	CL:0000576	55.96	gold quality
testis	UBERON:0000473	55.33	gold quality
left testis	UBERON:0004533	55.21	gold quality
right testis	UBERON:0004534	55.01	gold quality
placenta	UBERON:0001987	54.56	gold quality
islet of Langerhans	UBERON:0000006	54.22	gold quality
prefrontal cortex	UBERON:0000451	54.02	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.89	gold quality
tibial nerve	UBERON:0001323	53.70	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.46	gold quality
tonsil	UBERON:0002372	53.29	gold quality
primary visual cortex	UBERON:0002436	53.02	gold quality
bone marrow	UBERON:0002371	52.86	gold quality
gall bladder	UBERON:0002110	51.66	gold quality
blood	UBERON:0000178	51.04	silver quality
smooth muscle tissue	UBERON:0001135	51.04	gold quality
stomach	UBERON:0000945	50.25	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-HCAD-25	yes	17.08
E-ANND-3	no	1.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.