FZD4-DT

Summary

FZD4-DT (FZD4 divergent transcript, HGNC:54219) is a long non-coding RNA gene on chromosome 11q14.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54219
Approved symbol	FZD4-DT
Name	FZD4 divergent transcript
Location	11q14.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246523
Ensembl biotype	lncRNA
Entrez	100506368
RNAcentral	URS000075E5F0 — lncRNA, 1218 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 23 — 23 lncRNA

ENST00000499504, ENST00000531827, ENST00000662165, ENST00000687459, ENST00000688518, ENST00000797475, ENST00000797476, ENST00000797477, ENST00000797478, ENST00000797479, ENST00000797480, ENST00000797481, ENST00000797482, ENST00000797483, ENST00000797484, ENST00000797485, ENST00000797486, ENST00000797487, ENST00000797488, ENST00000797489, ENST00000797490, ENST00000797491, ENST00000797492

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499504 — 3 exons

Exon	Start	End
ENSE00001963187	86957982	86958026
ENSE00004184201	86955558	86955712
ENSE00004184218	86999876	87001009

Expression profiles

Bgee: expression breadth ubiquitous, 165 present calls, max score 86.31.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4029 / max 13.0835, expressed in 234 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
116137	0.4029	234

Top tissues by expression

228 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	86.31	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.96	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.46	gold quality
myocardium	UBERON:0002349	77.35	silver quality
apex of heart	UBERON:0002098	69.13	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.95	gold quality
colonic epithelium	UBERON:0000397	68.67	silver quality
cortical plate	UBERON:0005343	67.66	gold quality
muscle of leg	UBERON:0001383	67.59	gold quality
gastrocnemius	UBERON:0001388	67.40	gold quality
popliteal artery	UBERON:0002250	67.12	gold quality
tibial artery	UBERON:0007610	67.08	gold quality
tendon of biceps brachii	UBERON:0008188	66.67	gold quality
vena cava	UBERON:0004087	66.52	silver quality
descending thoracic aorta	UBERON:0002345	66.47	gold quality
heart left ventricle	UBERON:0002084	66.22	gold quality
left coronary artery	UBERON:0001626	66.21	gold quality
aorta	UBERON:0000947	66.18	gold quality
coronary artery	UBERON:0001621	65.66	gold quality
caput epididymis	UBERON:0004358	65.61	silver quality
cardiac ventricle	UBERON:0002082	65.57	gold quality
tendon	UBERON:0000043	65.55	gold quality
right coronary artery	UBERON:0001625	65.45	gold quality
heart	UBERON:0000948	65.44	gold quality
omental fat pad	UBERON:0010414	65.18	gold quality
peritoneum	UBERON:0002358	65.16	gold quality
thoracic aorta	UBERON:0001515	65.06	gold quality
ascending aorta	UBERON:0001496	64.99	gold quality
calcaneal tendon	UBERON:0003701	64.85	gold quality
adipose tissue of abdominal region	UBERON:0007808	64.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.