G2E3-AS1

Summary

G2E3-AS1 (G2E3 antisense RNA 1, HGNC:53463) is a long non-coding RNA gene on chromosome 14q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53463
Approved symbol	G2E3-AS1
Name	G2E3 antisense RNA 1
Location	14q12
Locus type	RNA, long non-coding
Status	Approved
Aliases	CAT1647, lincPRKD
Ensembl gene	ENSG00000257636
Ensembl biotype	lncRNA
Entrez	105370431
RNAcentral	URS0000CCE157 — lncRNA, 450 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000548631, ENST00000550118, ENST00000550680, ENST00000552511, ENST00000781340, ENST00000847973, ENST00000847974, ENST00000847975, ENST00000847976, ENST00000847977, ENST00000847978, ENST00000847979, ENST00000847980, ENST00000847981, ENST00000847982, ENST00000847983, ENST00000847984, ENST00000847985, ENST00000847986

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000548631 — 4 exons

Exon	Start	End
ENSE00002353565	30450360	30450692
ENSE00002387382	30474001	30474070
ENSE00002396229	30473522	30473599
ENSE00002426124	30451868	30451965

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 84.51.

Top tissues by expression

219 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.51	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.29	gold quality
colonic epithelium	UBERON:0000397	77.98	gold quality
bone marrow cell	CL:0002092	72.43	silver quality
sural nerve	UBERON:0015488	68.66	gold quality
adrenal tissue	UBERON:0018303	63.03	gold quality
left testis	UBERON:0004533	62.09	gold quality
right testis	UBERON:0004534	60.94	gold quality
testis	UBERON:0000473	60.86	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.84	silver quality
secondary oocyte	CL:0000655	58.09	gold quality
calcaneal tendon	UBERON:0003701	57.47	gold quality
monocyte	CL:0000576	54.45	silver quality
islet of Langerhans	UBERON:0000006	54.26	gold quality
pigmented layer of retina	UBERON:0001782	53.11	gold quality
mucosa of paranasal sinus	UBERON:0005030	52.96	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.83	gold quality
corpus callosum	UBERON:0002336	50.19	gold quality
prefrontal cortex	UBERON:0000451	49.87	gold quality
sperm	CL:0000019	49.72	gold quality
tendon	UBERON:0000043	49.18	gold quality
muscle of leg	UBERON:0001383	48.80	gold quality
tonsil	UBERON:0002372	48.69	silver quality
blood	UBERON:0000178	48.26	gold quality
right atrium auricular region	UBERON:0006631	48.20	gold quality
pancreas	UBERON:0001264	48.03	gold quality
body of pancreas	UBERON:0001150	47.63	gold quality
stomach	UBERON:0000945	47.60	gold quality
adult mammalian kidney	UBERON:0000082	47.40	gold quality
gastrocnemius	UBERON:0001388	47.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.04

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.