GABRA2-AS1

Summary

GABRA2-AS1 (GABRA2 antisense RNA 1, HGNC:40247) is a long non-coding RNA gene on chromosome 4p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40247
Approved symbol	GABRA2-AS1
Name	GABRA2 antisense RNA 1
Location	4p12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249330
Ensembl biotype	lncRNA
Entrez	144093401

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000502455, ENST00000651612

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502455 — 3 exons

Exon	Start	End
ENSE00002023086	46390885	46391008
ENSE00002048889	46390255	46390568
ENSE00002068286	46433078	46435772

Expression profiles

Bgee: expression breadth broad, 40 present calls, max score 96.89.

Top tissues by expression

40 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	96.89	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.78	silver quality
ventricular zone	UBERON:0003053	59.57	silver quality
ganglionic eminence	UBERON:0004023	57.12	silver quality
blood	UBERON:0000178	52.77	gold quality
nucleus accumbens	UBERON:0001882	52.65	gold quality
prefrontal cortex	UBERON:0000451	52.37	gold quality
temporal lobe	UBERON:0001871	51.80	gold quality
amygdala	UBERON:0001876	51.72	gold quality
Ammon’s horn	UBERON:0001954	50.22	gold quality
caudate nucleus	UBERON:0001873	50.16	gold quality
putamen	UBERON:0001874	50.13	gold quality
frontal cortex	UBERON:0001870	49.97	gold quality
anterior cingulate cortex	UBERON:0009835	49.87	gold quality
cerebral cortex	UBERON:0000956	49.77	gold quality
brain	UBERON:0000955	49.41	gold quality
Brodmann (1909) area 9	UBERON:0013540	49.39	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	49.00	gold quality
primary visual cortex	UBERON:0002436	48.95	silver quality
superior frontal gyrus	UBERON:0002661	48.49	silver quality
monocyte	CL:0000576	48.47	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	48.42	gold quality
right frontal lobe	UBERON:0002810	47.69	gold quality
cerebellar cortex	UBERON:0002129	46.60	silver quality
right hemisphere of cerebellum	UBERON:0014890	46.55	gold quality
cerebellar hemisphere	UBERON:0002245	46.44	silver quality
islet of Langerhans	UBERON:0000006	45.56	silver quality
gastrocnemius	UBERON:0001388	43.77	silver quality
muscle layer of sigmoid colon	UBERON:0035805	42.55	silver quality
adult mammalian kidney	UBERON:0000082	42.40	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.