GABRG3-AS1

Summary

GABRG3-AS1 (GABRG3 antisense RNA 1, HGNC:40249) is a long non-coding RNA gene on chromosome 15q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40249
Approved symbol	GABRG3-AS1
Name	GABRG3 antisense RNA 1
Location	15q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228740
Ensembl biotype	lncRNA
Entrez	101928869
RNAcentral	URS000075C3A9 — lncRNA, 855 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000439938, ENST00000657653, ENST00000660679, ENST00000663358, ENST00000720026, ENST00000720027

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439938 — 3 exons

Exon	Start	End
ENSE00001633206	27161022	27161319
ENSE00001726634	27158266	27158396
ENSE00001790086	27157615	27158155

Expression profiles

Bgee: expression breadth broad, 64 present calls, max score 96.67.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0557 / max 49.6193, expressed in 5 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
149040	0.0428	4
149042	0.0079	3
149041	0.0050	3

Top tissues by expression

177 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	96.67	gold quality
left testis	UBERON:0004533	91.69	gold quality
right testis	UBERON:0004534	90.61	gold quality
testis	UBERON:0000473	88.20	gold quality
islet of Langerhans	UBERON:0000006	80.26	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.94	gold quality
epithelial cell of pancreas	CL:0000083	79.33	gold quality
buccal mucosa cell	CL:0002336	76.84	gold quality
bone marrow cell	CL:0002092	75.65	silver quality
kidney epithelium	UBERON:0004819	74.54	gold quality
cardiac muscle of right atrium	UBERON:0003379	73.95	gold quality
left ventricle myocardium	UBERON:0006566	73.80	gold quality
ileal mucosa	UBERON:0000331	71.71	silver quality
tibialis anterior	UBERON:0001385	70.89	silver quality
upper arm skin	UBERON:0004263	70.11	gold quality
myocardium	UBERON:0002349	68.53	gold quality
adult organism	UBERON:0007023	65.96	gold quality
pancreatic ductal cell	CL:0002079	65.44	silver quality
quadriceps femoris	UBERON:0001377	64.27	gold quality
vastus lateralis	UBERON:0001379	63.56	gold quality
deltoid	UBERON:0001476	62.38	gold quality
endothelial cell	CL:0000115	61.88	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	61.59	gold quality
cartilage tissue	UBERON:0002418	61.58	gold quality
tendon of biceps brachii	UBERON:0008188	61.21	gold quality
superficial temporal artery	UBERON:0001614	60.36	gold quality
tendon	UBERON:0000043	59.46	gold quality
esophagus squamous epithelium	UBERON:0006920	58.98	gold quality
tibial nerve	UBERON:0001323	58.42	gold quality
caecum	UBERON:0001153	58.35	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-HCAD-25	yes	37.89
E-ANND-3	no	2.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.