GAPDH-AS1

Summary

GAPDH-AS1 (GAPDH antisense RNA 1, HGNC:58389) is a long non-coding RNA gene on chromosome 12p13.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58389
Approved symbol	GAPDH-AS1
Name	GAPDH antisense RNA 1
Location	12p13.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000269968
Ensembl biotype	lncRNA
Entrez	141725159

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000602946, ENST00000770643, ENST00000770644, ENST00000770645

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000602946 — 2 exons

Exon	Start	End
ENSE00003400616	6538141	6538370
ENSE00003414369	6537794	6537985

Expression profiles

Bgee: expression breadth ubiquitous, 139 present calls, max score 98.69.

Top tissues by expression

149 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	98.69	gold quality
colonic epithelium	UBERON:0000397	98.58	gold quality
primary visual cortex	UBERON:0002436	93.65	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.05	gold quality
hindlimb stylopod muscle	UBERON:0004252	92.35	gold quality
muscle tissue	UBERON:0002385	91.60	gold quality
skeletal muscle tissue	UBERON:0001134	90.80	gold quality
ventricular zone	UBERON:0003053	88.30	gold quality
superior frontal gyrus	UBERON:0002661	87.77	gold quality
epithelium of bronchus	UBERON:0002031	85.26	gold quality
tonsil	UBERON:0002372	85.03	gold quality
cortex of kidney	UBERON:0001225	84.13	gold quality
apex of heart	UBERON:0002098	83.97	gold quality
stromal cell of endometrium	CL:0002255	83.86	gold quality
vastus lateralis	UBERON:0001379	83.47	gold quality
bone marrow	UBERON:0002371	82.52	gold quality
ganglionic eminence	UBERON:0004023	82.49	gold quality
muscle of leg	UBERON:0001383	80.82	gold quality
endometrium epithelium	UBERON:0004811	80.47	gold quality
quadriceps femoris	UBERON:0001377	80.19	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.83	gold quality
liver	UBERON:0002107	79.61	gold quality
gastrocnemius	UBERON:0001388	79.54	gold quality
prefrontal cortex	UBERON:0000451	78.39	gold quality
kidney	UBERON:0002113	77.59	gold quality
sural nerve	UBERON:0015488	76.15	gold quality
cerebellar vermis	UBERON:0004720	75.21	gold quality
adult mammalian kidney	UBERON:0000082	73.33	gold quality
metanephric glomerulus	UBERON:0004736	73.15	gold quality
frontal cortex	UBERON:0001870	72.66	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	6149.19
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.