GARS1-DT

Summary

GARS1-DT (GARS1 divergent transcript, HGNC:48951) is a long non-coding RNA gene on chromosome 7p14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48951
Approved symbol	GARS1-DT
Name	GARS1 divergent transcript
Location	7p14.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC005154.6, AC005154.1
Ensembl gene	ENSG00000196295
Ensembl biotype	lncRNA
Entrez	401320
RNAcentral	URS000075D6DC — lncRNA, 3871 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 54 — 46 lncRNA, 8 retained_intron

ENST00000355837, ENST00000426529, ENST00000434399, ENST00000440438, ENST00000454922, ENST00000577889, ENST00000578245, ENST00000578293, ENST00000578572, ENST00000578994, ENST00000579024, ENST00000579174, ENST00000580440, ENST00000580902, ENST00000581665, ENST00000581794, ENST00000582145, ENST00000582549, ENST00000582733, ENST00000582838, ENST00000583664, ENST00000584023, ENST00000584108, ENST00000584199, ENST00000584372, ENST00000584621, ENST00000614950, ENST00000621272, ENST00000625565, ENST00000626245, ENST00000626902, ENST00000631229, ENST00000656284, ENST00000656943, ENST00000657049, ENST00000660767, ENST00000663031, ENST00000663462, ENST00000663944, ENST00000667129, ENST00000667137, ENST00000667338, ENST00000689508, ENST00000785588, ENST00000785589, ENST00000785590, ENST00000785591, ENST00000785592, ENST00000785593, ENST00000785594, ENST00000785595, ENST00000785596, ENST00000785597, ENST00000785598

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000355837 — 2 exons

Exon	Start	End
ENSE00001218435	30563723	30564617
ENSE00001415727	30548357	30562128

Expression profiles

Bgee: expression breadth ubiquitous, 239 present calls, max score 97.90.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 25.1699 / max 277.3082, expressed in 1813 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
83451	23.8407	1813
83450	0.4001	143
83452	0.3370	121
83447	0.3058	65
83446	0.2151	41
83445	0.0713	28

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adenohypophysis	UBERON:0002196	97.90	gold quality
right uterine tube	UBERON:0001302	97.85	gold quality
sural nerve	UBERON:0015488	97.19	gold quality
right lobe of thyroid gland	UBERON:0001119	96.86	gold quality
granulocyte	CL:0000094	96.74	gold quality
tibial nerve	UBERON:0001323	96.72	gold quality
right hemisphere of cerebellum	UBERON:0014890	96.69	gold quality
pituitary gland	UBERON:0000007	96.67	gold quality
left lobe of thyroid gland	UBERON:0001120	96.48	gold quality
bone marrow cell	CL:0002092	96.41	gold quality
cerebellar hemisphere	UBERON:0002245	96.41	gold quality
cerebellar cortex	UBERON:0002129	96.18	gold quality
mucosa of stomach	UBERON:0001199	95.90	gold quality
monocyte	CL:0000576	95.84	gold quality
lower esophagus muscularis layer	UBERON:0035833	95.75	gold quality
lower esophagus	UBERON:0013473	95.74	gold quality
right lung	UBERON:0002167	95.72	gold quality
left uterine tube	UBERON:0001303	95.67	gold quality
right frontal lobe	UBERON:0002810	95.61	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	95.61	gold quality
thyroid gland	UBERON:0002046	95.59	gold quality
small intestine Peyer’s patch	UBERON:0003454	95.58	gold quality
upper lobe of left lung	UBERON:0008952	95.57	gold quality
left ovary	UBERON:0002119	95.45	gold quality
muscle layer of sigmoid colon	UBERON:0035805	95.37	gold quality
colonic epithelium	UBERON:0000397	95.35	gold quality
spleen	UBERON:0002106	95.31	gold quality
right adrenal gland	UBERON:0001233	95.22	gold quality
leukocyte	CL:0000738	95.21	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	95.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.35

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.