GASK1B-AS1

Summary

GASK1B-AS1 (GASK1B antisense RNA 1, HGNC:53132) is a long non-coding RNA gene on chromosome 4q32.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53132
Approved symbol	GASK1B-AS1
Name	GASK1B antisense RNA 1
Location	4q32.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248429
Ensembl biotype	lncRNA
Entrez	285505
RNAcentral	URS00002D033D — lncRNA, 2917 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000503611, ENST00000505532, ENST00000508752, ENST00000509463, ENST00000514381, ENST00000763796, ENST00000803175, ENST00000803176, ENST00000803177, ENST00000803178

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503611 — 6 exons

Exon	Start	End
ENSE00002055808	158201412	158202877
ENSE00002057795	158198788	158198870
ENSE00002058736	158170752	158171480
ENSE00002062600	158179661	158179735
ENSE00002063054	158199088	158199486
ENSE00002081897	158172252	158172416

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 87.75.

FANTOM5 (CAGE): breadth broad, TPM avg 2.1101 / max 109.5974, expressed in 857 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
50268	1.1530	600
50266	0.3605	215
50269	0.3198	126
50267	0.2025	83
203398	0.0742	37

Top tissues by expression

135 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	87.75	gold quality
right adrenal gland	UBERON:0001233	86.72	gold quality
right adrenal gland cortex	UBERON:0035827	86.41	gold quality
left adrenal gland	UBERON:0001234	85.45	gold quality
adrenal gland	UBERON:0002369	84.76	gold quality
left adrenal gland cortex	UBERON:0035825	84.71	gold quality
monocyte	CL:0000576	84.69	gold quality
left ovary	UBERON:0002119	84.42	gold quality
ovary	UBERON:0000992	84.04	gold quality
leukocyte	CL:0000738	83.94	gold quality
thoracic aorta	UBERON:0001515	83.33	gold quality
ascending aorta	UBERON:0001496	83.29	gold quality
descending thoracic aorta	UBERON:0002345	83.07	gold quality
endometrium	UBERON:0001295	81.89	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.68	gold quality
right ovary	UBERON:0002118	81.27	gold quality
apex of heart	UBERON:0002098	81.05	gold quality
right coronary artery	UBERON:0001625	80.46	gold quality
smooth muscle tissue	UBERON:0001135	78.68	gold quality
sural nerve	UBERON:0015488	78.46	gold quality
heart left ventricle	UBERON:0002084	78.12	gold quality
heart	UBERON:0000948	77.82	gold quality
right atrium auricular region	UBERON:0006631	77.43	gold quality
body of uterus	UBERON:0009853	76.27	gold quality
tibial nerve	UBERON:0001323	76.24	gold quality
left coronary artery	UBERON:0001626	76.07	gold quality
thoracic mammary gland	UBERON:0005200	75.76	gold quality
left uterine tube	UBERON:0001303	75.45	gold quality
myometrium	UBERON:0001296	75.23	gold quality
stromal cell of endometrium	CL:0002255	74.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.