GBX2-AS1

Summary

GBX2-AS1 (GBX2 and ASB18 antisense RNA 1, HGNC:55714) is a long non-coding RNA gene on chromosome 2q37.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55714
Approved symbol	GBX2-AS1
Name	GBX2 and ASB18 antisense RNA 1
Location	2q37.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC079135.1
Ensembl gene	ENSG00000233611
Ensembl biotype	lncRNA
Entrez	121853074
RNAcentral	URS00026A2516 — lncRNA, 791 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000415226, ENST00000483218, ENST00000685281, ENST00000686834, ENST00000692565, ENST00000692928, ENST00000763428, ENST00000763429, ENST00000763430, ENST00000763431, ENST00000763432, ENST00000763433, ENST00000763434, ENST00000763435, ENST00000763436, ENST00000763437, ENST00000763438, ENST00000763439, ENST00000763440, ENST00000763441, ENST00000763442, ENST00000763443, ENST00000763444, ENST00000763445, ENST00000763446, ENST00000763447, ENST00000763448, ENST00000763449, ENST00000763450

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415226 — 4 exons

Exon	Start	End
ENSE00001595270	236167447	236167669
ENSE00001613151	236294773	236294927
ENSE00001695550	236277372	236277452
ENSE00001727331	236259507	236259599

Expression profiles

Bgee: expression breadth broad, 64 present calls, max score 84.49.

Top tissues by expression

64 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.49	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.16	gold quality
apex of heart	UBERON:0002098	65.71	gold quality
skeletal muscle tissue	UBERON:0001134	65.11	gold quality
sural nerve	UBERON:0015488	65.09	gold quality
heart left ventricle	UBERON:0002084	59.18	gold quality
monocyte	CL:0000576	58.88	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.87	gold quality
muscle of leg	UBERON:0001383	56.45	gold quality
heart	UBERON:0000948	55.93	gold quality
placenta	UBERON:0001987	54.65	gold quality
gastrocnemius	UBERON:0001388	54.36	gold quality
liver	UBERON:0002107	53.99	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.59	gold quality
blood	UBERON:0000178	49.45	silver quality
islet of Langerhans	UBERON:0000006	48.76	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	48.70	gold quality
multicellular organism	UBERON:0000468	48.60	gold quality
primary visual cortex	UBERON:0002436	47.73	silver quality
right atrium auricular region	UBERON:0006631	47.69	gold quality
tibial artery	UBERON:0007610	47.32	gold quality
popliteal artery	UBERON:0002250	47.27	gold quality
lung	UBERON:0002048	46.07	silver quality
calcaneal tendon	UBERON:0003701	45.84	silver quality
omental fat pad	UBERON:0010414	45.78	gold quality
substantia nigra	UBERON:0002038	45.74	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.61	silver quality
thoracic mammary gland	UBERON:0005200	45.25	gold quality
cortex of kidney	UBERON:0001225	44.89	silver quality
hypothalamus	UBERON:0001898	44.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.