GCLC-AS1

Summary

GCLC-AS1 (GCLC antisense RNA 1, HGNC:56649) is a long non-coding RNA gene on chromosome 6p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56649
Approved symbol	GCLC-AS1
Name	GCLC antisense RNA 1
Location	6p12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL033397.2
Ensembl gene	ENSG00000249379
Ensembl biotype	lncRNA
Entrez	105375095
RNAcentral	URS00026A1FE6 — lncRNA, 721 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000508884, ENST00000655377, ENST00000789578, ENST00000789579, ENST00000789580, ENST00000789581, ENST00000789582

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508884 — 3 exons

Exon	Start	End
ENSE00002044559	53506798	53506928
ENSE00003858242	53503109	53503328
ENSE00003862052	53506160	53506434

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 83.86.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.86	gold quality
left testis	UBERON:0004533	74.40	gold quality
right testis	UBERON:0004534	73.98	gold quality
testis	UBERON:0000473	73.79	gold quality
colonic epithelium	UBERON:0000397	73.47	silver quality
right lobe of liver	UBERON:0001114	71.36	gold quality
right uterine tube	UBERON:0001302	70.74	gold quality
liver	UBERON:0002107	69.89	gold quality
lower esophagus mucosa	UBERON:0035834	69.41	gold quality
bone marrow	UBERON:0002371	69.27	gold quality
subcutaneous adipose tissue	UBERON:0002190	68.51	gold quality
vagina	UBERON:0000996	68.42	gold quality
sural nerve	UBERON:0015488	68.04	silver quality
mucosa of stomach	UBERON:0001199	66.21	gold quality
esophagus mucosa	UBERON:0002469	66.07	gold quality
prostate gland	UBERON:0002367	65.64	gold quality
adipose tissue	UBERON:0001013	65.44	gold quality
skin of abdomen	UBERON:0001416	65.24	gold quality
urinary bladder	UBERON:0001255	64.44	gold quality
bone marrow cell	CL:0002092	64.34	silver quality
stromal cell of endometrium	CL:0002255	64.17	gold quality
esophagus	UBERON:0001043	64.14	gold quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
left lobe of thyroid gland	UBERON:0001120	64.12	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.09	gold quality
corpus callosum	UBERON:0002336	63.77	gold quality
minor salivary gland	UBERON:0001830	63.15	gold quality
uterine cervix	UBERON:0000002	63.11	gold quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
thyroid gland	UBERON:0002046	62.93	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.