GCSAML-AS1

Summary

GCSAML-AS1 (GCSAML antisense RNA 1, HGNC:41244) is a long non-coding RNA gene on chromosome 1q44.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41244
Approved symbol	GCSAML-AS1
Name	GCSAML antisense RNA 1
Location	1q44
Locus type	RNA, long non-coding
Status	Approved
Entrez	148824
RNAcentral	URS000075A3EE — lncRNA, 1931 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000005905 (1:247531025 G>C,T), RS1000236980 (1:247524698 T>G), RS1000610833 (1:247526153 T>G), RS1001275832 (1:247529735 T>G), RS1001845824 (1:247525729 TCTG>T), RS1002281482 (1:247527990 G>A), RS1002333936 (1:247527738 G>A,C,T), RS1003011278 (1:247530818 C>A,G), RS1003255799 (1:247524247 G>C), RS1003337060 (1:247528324 T>C), RS1003444088 (1:247528976 G>C), RS1003464363 (1:247524618 T>C), RS1003464952 (1:247527006 T>C), RS1003848813 (1:247527510 G>T), RS1004581614 (1:247529519 G>A,C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Aflatoxin B1	decreases methylation	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.