GK-AS1

Summary

GK-AS1 (GK antisense RNA 1, HGNC:40255) is a long non-coding RNA gene on chromosome Xp21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40255
Approved symbol	GK-AS1
Name	GK antisense RNA 1
Location	Xp21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243055
Ensembl biotype	lncRNA
Entrez	100873902
RNAcentral	URS0002123180 — lncRNA, 18036 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000464659

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000464659 — 2 exons

Exon	Start	End
ENSE00001837836	30723711	30724174
ENSE00001952884	30699998	30700184

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 85.53.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.53	gold quality
blood	UBERON:0000178	82.97	gold quality
colonic epithelium	UBERON:0000397	80.34	gold quality
liver	UBERON:0002107	76.43	gold quality
stromal cell of endometrium	CL:0002255	76.37	gold quality
adrenal tissue	UBERON:0018303	74.87	gold quality
right lobe of liver	UBERON:0001114	74.11	gold quality
bone marrow cell	CL:0002092	73.14	gold quality
vermiform appendix	UBERON:0001154	72.97	gold quality
duodenum	UBERON:0002114	72.76	gold quality
upper lobe of left lung	UBERON:0008952	71.23	gold quality
right lung	UBERON:0002167	70.78	gold quality
monocyte	CL:0000576	70.57	gold quality
leukocyte	CL:0000738	70.32	gold quality
gall bladder	UBERON:0002110	68.99	gold quality
lung	UBERON:0002048	67.26	gold quality
ganglionic eminence	UBERON:0004023	65.29	gold quality
ventricular zone	UBERON:0003053	64.94	gold quality
bone marrow	UBERON:0002371	64.75	gold quality
small intestine	UBERON:0002108	64.62	gold quality
spleen	UBERON:0002106	64.40	gold quality
small intestine Peyer’s patch	UBERON:0003454	63.49	gold quality
granulocyte	CL:0000094	63.18	gold quality
minor salivary gland	UBERON:0001830	62.94	gold quality
right adrenal gland cortex	UBERON:0035827	62.89	gold quality
saliva-secreting gland	UBERON:0001044	62.75	gold quality
adrenal gland	UBERON:0002369	62.46	gold quality
left adrenal gland cortex	UBERON:0035825	62.33	gold quality
tonsil	UBERON:0002372	62.19	gold quality
cortex of kidney	UBERON:0001225	62.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.87

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.