GK-IT1

Summary

GK-IT1 (GK intronic transcript 1, HGNC:41339) is a long non-coding RNA gene on chromosome Xp21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41339
Approved symbol	GK-IT1
Name	GK intronic transcript 1
Location	Xp21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229331
Ensembl biotype	lncRNA
Entrez	106480740
RNAcentral	URS00001DEBB7 — lncRNA, 397 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000441146

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000441146 — 2 exons

Exon	Start	End
ENSE00001591621	30671635	30671894
ENSE00001609072	30672030	30672166

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 83.39.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.39	gold quality
blood	UBERON:0000178	75.54	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.89	gold quality
muscle tissue	UBERON:0002385	73.63	gold quality
bone marrow cell	CL:0002092	72.18	silver quality
adrenal tissue	UBERON:0018303	66.47	gold quality
liver	UBERON:0002107	66.43	gold quality
vermiform appendix	UBERON:0001154	65.25	gold quality
skeletal muscle tissue	UBERON:0001134	63.96	silver quality
duodenum	UBERON:0002114	61.88	gold quality
bone marrow	UBERON:0002371	61.73	gold quality
right lobe of liver	UBERON:0001114	60.46	gold quality
monocyte	CL:0000576	60.00	gold quality
leukocyte	CL:0000738	59.54	gold quality
lymph node	UBERON:0000029	59.10	gold quality
upper lobe of left lung	UBERON:0008952	57.87	gold quality
lung	UBERON:0002048	57.69	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.63	gold quality
tonsil	UBERON:0002372	57.13	gold quality
gall bladder	UBERON:0002110	56.67	gold quality
prefrontal cortex	UBERON:0000451	56.58	gold quality
adult mammalian kidney	UBERON:0000082	56.30	gold quality
kidney	UBERON:0002113	55.90	gold quality
cortex of kidney	UBERON:0001225	55.75	gold quality
islet of Langerhans	UBERON:0000006	55.74	gold quality
left uterine tube	UBERON:0001303	55.59	gold quality
primary visual cortex	UBERON:0002436	55.12	gold quality
placenta	UBERON:0001987	55.05	gold quality
left adrenal gland cortex	UBERON:0035825	54.71	gold quality
granulocyte	CL:0000094	54.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.