GLIDR

Summary

GLIDR (glioblastoma down-regulated RNA, HGNC:48823) is a long non-coding RNA gene on chromosome 9p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48823
Approved symbol	GLIDR
Name	glioblastoma down-regulated RNA
Location	9p12
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC21881, TCONS_00015562, FAM88A
Ensembl gene	ENSG00000278175
Ensembl biotype	lncRNA
OMIM	621292
Entrez	389741
RNAcentral	URS00007E3B59 — lncRNA, 2682 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 128 — 128 lncRNA

ENST00000618092, ENST00000625350, ENST00000627065, ENST00000638724, ENST00000640674, ENST00000656945, ENST00000657066, ENST00000660231, ENST00000663590, ENST00000665892, ENST00000666618, ENST00000666906, ENST00000667968, ENST00000670314, ENST00000685044, ENST00000685667, ENST00000686124, ENST00000686377, ENST00000686441, ENST00000686447, ENST00000686915, ENST00000687737, ENST00000687919, ENST00000688435, ENST00000689331, ENST00000689603, ENST00000689701, ENST00000689933, ENST00000691529, ENST00000691672, ENST00000691680, ENST00000691757, ENST00000691877, ENST00000692061, ENST00000692088, ENST00000701054, ENST00000701143, ENST00000701295, ENST00000701685, ENST00000701723, ENST00000701786, ENST00000701809, ENST00000701861, ENST00000701871, ENST00000839067, ENST00000839068, ENST00000839069, ENST00000839070, ENST00000839071, ENST00000839072, ENST00000839073, ENST00000839074, ENST00000839075, ENST00000839076, ENST00000839077, ENST00000839078, ENST00000839079, ENST00000839080, ENST00000839081, ENST00000839082, ENST00000839083, ENST00000839084, ENST00000839085, ENST00000839086, ENST00000839087, ENST00000839088, ENST00000839089, ENST00000839090, ENST00000839091, ENST00000839092, ENST00000839093, ENST00000839094, ENST00000839095, ENST00000839096, ENST00000839097, ENST00000839098, ENST00000839099, ENST00000839100, ENST00000839101, ENST00000839102, ENST00000839103, ENST00000839104, ENST00000839105, ENST00000839106, ENST00000839107, ENST00000839108, ENST00000839109, ENST00000839110, ENST00000839111, ENST00000839112, ENST00000839113, ENST00000839114, ENST00000839115, ENST00000839116, ENST00000839117, ENST00000839118, ENST00000839119, ENST00000839120, ENST00000839121, ENST00000839122, ENST00000839123, ENST00000839124, ENST00000839125, ENST00000839126, ENST00000839127, ENST00000839128, ENST00000839129, ENST00000839130, ENST00000839131, ENST00000839132, ENST00000839133, ENST00000839134, ENST00000839135, ENST00000839136, ENST00000839137, ENST00000839138, ENST00000839139, ENST00000839140, ENST00000839141, ENST00000839142, ENST00000839143, ENST00000839144, ENST00000839145, ENST00000839146, ENST00000839147, ENST00000839148, ENST00000839149, ENST00000839150

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000618092 — 2 exons

Exon	Start	End
ENSE00004260963	39809731	39810089
ENSE00004261068	39807359	39809633

Expression profiles

Bgee: expression breadth ubiquitous, 248 present calls, max score 94.12.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.9660 / max 48.3036, expressed in 1306 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
100780	2.6964	1273
100779	0.2696	134

Top tissues by expression

255 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
endothelial cell	CL:0000115	94.12	gold quality
oviduct epithelium	UBERON:0004804	91.50	gold quality
sural nerve	UBERON:0015488	91.23	gold quality
buccal mucosa cell	CL:0002336	90.96	gold quality
pituitary gland	UBERON:0000007	89.84	gold quality
adenohypophysis	UBERON:0002196	89.75	gold quality
ganglionic eminence	UBERON:0004023	89.55	gold quality
ventricular zone	UBERON:0003053	89.21	gold quality
apex of heart	UBERON:0002098	88.94	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	88.46	gold quality
spinal cord	UBERON:0002240	87.77	gold quality
left adrenal gland cortex	UBERON:0035825	86.79	gold quality
right adrenal gland	UBERON:0001233	86.78	gold quality
germinal epithelium of ovary	UBERON:0001304	86.65	gold quality
adrenal cortex	UBERON:0001235	86.37	gold quality
left adrenal gland	UBERON:0001234	86.19	gold quality
epithelium of nasopharynx	UBERON:0001951	85.95	gold quality
right atrium auricular region	UBERON:0006631	85.73	gold quality
heart left ventricle	UBERON:0002084	85.72	gold quality
tibial nerve	UBERON:0001323	85.68	gold quality
cardiac ventricle	UBERON:0002082	85.61	gold quality
right adrenal gland cortex	UBERON:0035827	85.53	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.08	gold quality
substantia nigra	UBERON:0002038	84.99	gold quality
lateral globus pallidus	UBERON:0002476	84.93	gold quality
right uterine tube	UBERON:0001302	84.90	gold quality
right lobe of thyroid gland	UBERON:0001119	84.88	gold quality
adrenal gland	UBERON:0002369	84.69	gold quality
midbrain	UBERON:0001891	84.62	gold quality
body of pancreas	UBERON:0001150	84.61	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.48

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• Increased GLIDR expression is associated with prostate cancer. (PMID:28211799)
• Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis. (PMID:34369267)
• GLIDR promotes the aggressiveness progression of prostate cancer cells by sponging miR-128-3p. (PMID:36709726)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.