GLIS2-AS1

Summary

GLIS2-AS1 (GLIS2 antisense RNA 1, HGNC:51381) is a long non-coding RNA gene on chromosome 16p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51381
Approved symbol	GLIS2-AS1
Name	GLIS2 antisense RNA 1
Location	16p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000262686
Ensembl biotype	lncRNA
Entrez	101926896
RNAcentral	URS000075C229 — lncRNA, 359 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000576080, ENST00000777335, ENST00000777336, ENST00000777337, ENST00000777338, ENST00000777339, ENST00000777340, ENST00000777341, ENST00000777342, ENST00000777343, ENST00000777344, ENST00000777345

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000576080 — 4 exons

Exon	Start	End
ENSE00002665496	4325270	4325354
ENSE00002667730	4326430	4326494
ENSE00004145964	4324647	4324775
ENSE00004145973	4328260	4328405

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 91.57.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	91.57	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.75	gold quality
nucleus accumbens	UBERON:0001882	80.46	gold quality
putamen	UBERON:0001874	79.98	gold quality
caudate nucleus	UBERON:0001873	79.05	gold quality
bone marrow cell	CL:0002092	77.18	gold quality
cortical plate	UBERON:0005343	75.04	gold quality
apex of heart	UBERON:0002098	75.03	gold quality
Ammon’s horn	UBERON:0001954	72.27	gold quality
heart left ventricle	UBERON:0002084	72.14	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.84	gold quality
brain	UBERON:0000955	71.68	gold quality
ventricular zone	UBERON:0003053	71.59	gold quality
cerebellar hemisphere	UBERON:0002245	71.58	gold quality
adult mammalian kidney	UBERON:0000082	71.47	gold quality
cerebellar cortex	UBERON:0002129	71.35	gold quality
cerebellum	UBERON:0002037	71.22	gold quality
pituitary gland	UBERON:0000007	71.14	gold quality
right adrenal gland	UBERON:0001233	71.11	gold quality
ganglionic eminence	UBERON:0004023	70.77	gold quality
thyroid gland	UBERON:0002046	70.61	gold quality
right lobe of thyroid gland	UBERON:0001119	70.57	gold quality
right adrenal gland cortex	UBERON:0035827	70.56	gold quality
left lobe of thyroid gland	UBERON:0001120	70.43	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.37	gold quality
left adrenal gland	UBERON:0001234	70.30	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.27	gold quality
left adrenal gland cortex	UBERON:0035825	70.24	gold quality
cortex of kidney	UBERON:0001225	70.17	gold quality
kidney	UBERON:0002113	70.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.