GLIS3-AS1

Summary

GLIS3-AS1 (GLIS3 antisense RNA 1, HGNC:28260) is a long non-coding RNA gene on chromosome 9p24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28260
Approved symbol	GLIS3-AS1
Name	GLIS3 antisense RNA 1
Location	9p24.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC16153
Ensembl gene	ENSG00000237009
Ensembl biotype	lncRNA
Entrez	84850
RNAcentral	URS000075EB77 — lncRNA, 730 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000451340

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000451340 — 2 exons

Exon	Start	End
ENSE00004190863	3900833	3901252
ENSE00004190864	3898642	3898959

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 86.06.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0231 / max 13.2504, expressed in 6 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
95888	0.0231	6

Top tissues by expression

218 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.06	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.43	gold quality
colonic epithelium	UBERON:0000397	64.96	silver quality
sperm	CL:0000019	63.94	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.98	gold quality
buccal mucosa cell	CL:0002336	61.91	gold quality
tendon of biceps brachii	UBERON:0008188	59.91	gold quality
nasal cavity mucosa	UBERON:0001826	57.02	gold quality
left lobe of thyroid gland	UBERON:0001120	56.63	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.33	gold quality
islet of Langerhans	UBERON:0000006	56.30	gold quality
descending thoracic aorta	UBERON:0002345	56.19	gold quality
thyroid gland	UBERON:0002046	56.03	gold quality
cartilage tissue	UBERON:0002418	55.74	gold quality
right lobe of thyroid gland	UBERON:0001119	55.51	gold quality
right uterine tube	UBERON:0001302	54.34	gold quality
parotid gland	UBERON:0001831	54.26	gold quality
oviduct epithelium	UBERON:0004804	53.86	silver quality
decidua	UBERON:0002450	53.73	gold quality
right lobe of liver	UBERON:0001114	53.19	gold quality
smooth muscle tissue	UBERON:0001135	52.67	gold quality
omental fat pad	UBERON:0010414	52.57	gold quality
peritoneum	UBERON:0002358	52.52	gold quality
right lung	UBERON:0002167	52.10	gold quality
adipose tissue of abdominal region	UBERON:0007808	51.70	gold quality
pancreas	UBERON:0001264	51.61	gold quality
mammalian vulva	UBERON:0000997	51.28	gold quality
ascending aorta	UBERON:0001496	50.65	gold quality
thoracic aorta	UBERON:0001515	50.53	gold quality
small intestine Peyer’s patch	UBERON:0003454	50.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.