GLIS3-AS2

Summary

GLIS3-AS2 (GLIS3 antisense RNA 2, HGNC:55796) is a long non-coding RNA gene on chromosome 9p24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55796
Approved symbol	GLIS3-AS2
Name	GLIS3 antisense RNA 2
Location	9p24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228322
Ensembl biotype	lncRNA
Entrez	107986989
RNAcentral	URS00026A1BCC — lncRNA, 530 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000440674

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440674 — 2 exons

Exon	Start	End
ENSE00001679822	4299390	4299423
ENSE00001736146	4305208	4306046

Expression profiles

Bgee: expression breadth broad, 91 present calls, max score 86.37.

Top tissues by expression

194 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.37	gold quality
stromal cell of endometrium	CL:0002255	62.62	gold quality
right uterine tube	UBERON:0001302	62.13	gold quality
ventricular zone	UBERON:0003053	61.80	gold quality
lower lobe of lung	UBERON:0008949	57.57	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	53.80	gold quality
islet of Langerhans	UBERON:0000006	53.39	gold quality
hindlimb stylopod muscle	UBERON:0004252	52.44	silver quality
pancreas	UBERON:0001264	52.35	gold quality
body of pancreas	UBERON:0001150	52.04	gold quality
right lobe of thyroid gland	UBERON:0001119	50.61	gold quality
thyroid gland	UBERON:0002046	49.43	gold quality
right lobe of liver	UBERON:0001114	48.76	silver quality
left lobe of thyroid gland	UBERON:0001120	48.76	gold quality
prefrontal cortex	UBERON:0000451	47.73	silver quality
endocervix	UBERON:0000458	47.30	gold quality
muscle of leg	UBERON:0001383	46.96	silver quality
fallopian tube	UBERON:0003889	46.49	gold quality
gastrocnemius	UBERON:0001388	46.48	silver quality
adult mammalian kidney	UBERON:0000082	46.23	gold quality
gall bladder	UBERON:0002110	46.19	gold quality
left ovary	UBERON:0002119	45.95	silver quality
rectum	UBERON:0001052	45.84	gold quality
nasal cavity mucosa	UBERON:0001826	45.68	gold quality
right ovary	UBERON:0002118	45.32	silver quality
liver	UBERON:0002107	44.97	silver quality
Brodmann (1909) area 9	UBERON:0013540	44.61	gold quality
lymph node	UBERON:0000029	44.60	silver quality
ovary	UBERON:0000992	44.21	silver quality
ascending aorta	UBERON:0001496	43.83	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.