GNAO1-DT

Summary

GNAO1-DT (GNAO1 divergent transcript, HGNC:27543) is a long non-coding RNA gene on chromosome 16q13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27543
Approved symbol	GNAO1-DT
Name	GNAO1 divergent transcript
Location	16q13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246379
Ensembl biotype	lncRNA
Entrez	283856
RNAcentral	URS00001F7DF8 — lncRNA, 2678 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 47 — 47 lncRNA

ENST00000501259, ENST00000565155, ENST00000565441, ENST00000567929, ENST00000569025, ENST00000648729, ENST00000654562, ENST00000657483, ENST00000661960, ENST00000662188, ENST00000662870, ENST00000663751, ENST00000664309, ENST00000665141, ENST00000668774, ENST00000715694, ENST00000825388, ENST00000825389, ENST00000825390, ENST00000825391, ENST00000825392, ENST00000825393, ENST00000825394, ENST00000825395, ENST00000825396, ENST00000825397, ENST00000825398, ENST00000825399, ENST00000825400, ENST00000825401, ENST00000825402, ENST00000825403, ENST00000825404, ENST00000825405, ENST00000825406, ENST00000825407, ENST00000825408, ENST00000825409, ENST00000825410, ENST00000825411, ENST00000825412, ENST00000825413, ENST00000825414, ENST00000825415, ENST00000825416, ENST00000825417, ENST00000825418

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501259 — 5 exons

Exon	Start	End
ENSE00001967950	56101046	56101212
ENSE00001969604	56092987	56093518
ENSE00001984446	56189502	56191094
ENSE00001988860	56187603	56187700
ENSE00001988969	56102032	56102319

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 86.72.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	86.72	gold quality
left testis	UBERON:0004533	86.10	gold quality
testis	UBERON:0000473	82.50	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.38	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.62	gold quality
cortical plate	UBERON:0005343	76.22	gold quality
sural nerve	UBERON:0015488	76.07	gold quality
ganglionic eminence	UBERON:0004023	73.74	gold quality
prefrontal cortex	UBERON:0000451	71.96	gold quality
islet of Langerhans	UBERON:0000006	71.65	gold quality
calcaneal tendon	UBERON:0003701	71.61	gold quality
ventricular zone	UBERON:0003053	71.49	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.42	gold quality
anterior cingulate cortex	UBERON:0009835	70.75	gold quality
right frontal lobe	UBERON:0002810	70.67	gold quality
colonic epithelium	UBERON:0000397	69.71	silver quality
amygdala	UBERON:0001876	69.69	gold quality
popliteal artery	UBERON:0002250	69.49	gold quality
tibial artery	UBERON:0007610	69.48	gold quality
putamen	UBERON:0001874	69.11	gold quality
Brodmann (1909) area 9	UBERON:0013540	68.87	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.68	gold quality
spinal cord	UBERON:0002240	68.64	gold quality
hypothalamus	UBERON:0001898	68.53	gold quality
right atrium auricular region	UBERON:0006631	68.37	gold quality
muscle layer of sigmoid colon	UBERON:0035805	68.21	gold quality
caudate nucleus	UBERON:0001873	68.09	gold quality
cerebellar cortex	UBERON:0002129	67.82	gold quality
cerebellar hemisphere	UBERON:0002245	67.82	gold quality
cardiac atrium	UBERON:0002081	67.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.36

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.