GP6-AS1

Summary

GP6-AS1 (GP6 antisense RNA 1, HGNC:55305) is a long non-coding RNA gene on chromosome 19q13.42.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55305
Approved symbol	GP6-AS1
Name	GP6 antisense RNA 1
Location	19q13.42
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267265
Ensembl biotype	lncRNA
Entrez	107985325
RNAcentral	URS0002A28138 — lncRNA, 1351 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 21 — 21 lncRNA

ENST00000586845, ENST00000586961, ENST00000593060, ENST00000690314, ENST00000778584, ENST00000778585, ENST00000778586, ENST00000778587, ENST00000778588, ENST00000778589, ENST00000778590, ENST00000778591, ENST00000778592, ENST00000778593, ENST00000778594, ENST00000778595, ENST00000778596, ENST00000778597, ENST00000778598, ENST00000778599, ENST00000778600

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000586845 — 3 exons

Exon	Start	End
ENSE00002793486	55042832	55043251
ENSE00002840711	55006417	55006464
ENSE00002926512	55006205	55006289

Expression profiles

Bgee: expression breadth ubiquitous, 164 present calls, max score 94.42.

Top tissues by expression

255 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	94.42	gold quality
tendon of biceps brachii	UBERON:0008188	84.17	silver quality
skin of leg	UBERON:0001511	82.49	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.43	silver quality
lower esophagus mucosa	UBERON:0035834	81.44	gold quality
skin of abdomen	UBERON:0001416	81.33	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.48	gold quality
esophagus mucosa	UBERON:0002469	78.32	gold quality
zone of skin	UBERON:0000014	78.09	gold quality
apex of heart	UBERON:0002098	76.80	gold quality
vagina	UBERON:0000996	75.71	gold quality
ectocervix	UBERON:0012249	75.71	gold quality
minor salivary gland	UBERON:0001830	75.59	gold quality
right lobe of thyroid gland	UBERON:0001119	75.31	gold quality
left lobe of thyroid gland	UBERON:0001120	74.83	gold quality
transverse colon	UBERON:0001157	74.82	gold quality
heart left ventricle	UBERON:0002084	74.52	gold quality
esophagus	UBERON:0001043	74.44	gold quality
body of stomach	UBERON:0001161	74.44	gold quality
rectum	UBERON:0001052	74.32	gold quality
saliva-secreting gland	UBERON:0001044	73.96	gold quality
cardiac ventricle	UBERON:0002082	73.85	gold quality
thyroid gland	UBERON:0002046	73.81	gold quality
monocyte	CL:0000576	73.79	gold quality
leukocyte	CL:0000738	73.75	gold quality
mucosa of transverse colon	UBERON:0004991	73.64	gold quality
ventricular zone	UBERON:0003053	73.62	gold quality
stromal cell of endometrium	CL:0002255	73.47	gold quality
right atrium auricular region	UBERON:0006631	73.36	gold quality
body of pancreas	UBERON:0001150	73.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.