GPC1-AS1

Summary

GPC1-AS1 (GPC1 antisense RNA 1, HGNC:56102) is a long non-coding RNA gene on chromosome 2q37.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56102
Approved symbol	GPC1-AS1
Name	GPC1 antisense RNA 1
Location	2q37.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000218416
Ensembl biotype	lncRNA
Entrez	100130449
RNAcentral	URS0000E60B3F — lncRNA, 959 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 15 lncRNA, 2 retained_intron

ENST00000404327, ENST00000404891, ENST00000471662, ENST00000538012, ENST00000824016, ENST00000824017, ENST00000824018, ENST00000824019, ENST00000824020, ENST00000824021, ENST00000824022, ENST00000824023, ENST00000824024, ENST00000824025, ENST00000824026, ENST00000824027, ENST00000824028

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000404327 — 3 exons

Exon	Start	End
ENSE00001547987	240450611	240450922
ENSE00004232890	240449379	240449921
ENSE00004232905	240456597	240456732

Expression profiles

Bgee: expression breadth ubiquitous, 184 present calls, max score 90.39.

Top tissues by expression

274 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
Brodmann (1909) area 10	UBERON:0013541	90.39	gold quality
paraflocculus	UBERON:0005351	88.69	gold quality
lower esophagus mucosa	UBERON:0035834	87.97	gold quality
frontal pole	UBERON:0002795	87.83	gold quality
placenta	UBERON:0001987	87.21	gold quality
middle frontal gyrus	UBERON:0002702	86.63	gold quality
endometrium epithelium	UBERON:0004811	83.11	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.31	gold quality
cortical plate	UBERON:0005343	79.81	gold quality
right hemisphere of cerebellum	UBERON:0014890	78.52	gold quality
amniotic fluid	UBERON:0000173	78.00	silver quality
right frontal lobe	UBERON:0002810	77.71	gold quality
cerebellar hemisphere	UBERON:0002245	77.08	gold quality
esophagus mucosa	UBERON:0002469	76.92	gold quality
cerebellar cortex	UBERON:0002129	76.75	gold quality
anterior cingulate cortex	UBERON:0009835	76.28	gold quality
cingulate cortex	UBERON:0003027	76.26	gold quality
sural nerve	UBERON:0015488	76.21	gold quality
nucleus accumbens	UBERON:0001882	75.92	gold quality
cerebellum	UBERON:0002037	74.27	gold quality
minor salivary gland	UBERON:0001830	73.31	gold quality
prostate gland	UBERON:0002367	73.06	gold quality
palpebral conjunctiva	UBERON:0001812	72.98	silver quality
skin of abdomen	UBERON:0001416	72.68	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.56	gold quality
Brodmann (1909) area 9	UBERON:0013540	72.54	gold quality
amygdala	UBERON:0001876	71.94	gold quality
nasal cavity epithelium	UBERON:0005384	71.18	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	71.11	gold quality
ganglionic eminence	UBERON:0004023	70.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.