GPC3-AS1

Summary

GPC3-AS1 (GPC3 antisense RNA 1, HGNC:52897) is a long non-coding RNA gene on chromosome Xq26.2.

At a glance

• Gene type: non-coding (TEC) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52897
Approved symbol	GPC3-AS1
Name	GPC3 antisense RNA 1
Location	Xq26.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286096
Ensembl biotype	TEC
Entrez	110806308
RNAcentral	URS0000BC45AA — lncRNA, 479 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 TEC

ENST00000651551

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000651551 — 1 exons

Exon	Start	End
ENSE00003851036	133897443	133897934

Expression profiles

Bgee: expression breadth broad, 34 present calls, max score 83.50.

Top tissues by expression

165 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	83.50	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.32	gold quality
islet of Langerhans	UBERON:0000006	78.53	gold quality
pancreatic ductal cell	CL:0002079	77.19	gold quality
tibialis anterior	UBERON:0001385	76.56	silver quality
ileal mucosa	UBERON:0000331	75.65	silver quality
colonic epithelium	UBERON:0000397	73.88	gold quality
kidney epithelium	UBERON:0004819	72.76	gold quality
myocardium	UBERON:0002349	69.46	gold quality
left ventricle myocardium	UBERON:0006566	69.01	gold quality
cardiac muscle of right atrium	UBERON:0003379	68.55	gold quality
gastrocnemius	UBERON:0001388	66.20	silver quality
upper arm skin	UBERON:0004263	66.17	gold quality
epithelial cell of pancreas	CL:0000083	65.36	silver quality
mucosa of paranasal sinus	UBERON:0005030	65.22	gold quality
cardiac atrium	UBERON:0002081	65.06	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	64.46	gold quality
quadriceps femoris	UBERON:0001377	64.12	gold quality
parotid gland	UBERON:0001831	63.33	gold quality
nasal cavity epithelium	UBERON:0005384	62.98	gold quality
vastus lateralis	UBERON:0001379	62.29	gold quality
tibia	UBERON:0000979	62.19	silver quality
metanephros	UBERON:0000081	61.86	gold quality
Brodmann (1909) area 46	UBERON:0006483	61.66	gold quality
trabecular bone tissue	UBERON:0002483	61.28	gold quality
saliva-secreting gland	UBERON:0001044	60.34	gold quality
biceps brachii	UBERON:0001507	59.92	gold quality
amniotic fluid	UBERON:0000173	59.74	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	59.62	gold quality
skin of hip	UBERON:0001554	59.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.