GPC5-AS1

Summary

GPC5-AS1 (GPC5 antisense RNA 1, HGNC:39886) is a long non-coding RNA gene on chromosome 13q31.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39886
Approved symbol	GPC5-AS1
Name	GPC5 antisense RNA 1
Location	13q31.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235984
Ensembl biotype	lncRNA
Entrez	100873969
RNAcentral	URS000075DA3D — lncRNA, 394 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000419288, ENST00000451897

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419288 — 4 exons

Exon	Start	End
ENSE00001677521	92709489	92709573
ENSE00001713634	92721534	92721614
ENSE00001722227	92701389	92701516
ENSE00001757219	92705961	92706059

Expression profiles

Bgee: expression breadth broad, 98 present calls, max score 91.31.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0962 / max 55.3933, expressed in 27 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
137816	0.0534	25
137817	0.0289	10
137819	0.0077	2
137818	0.0063	1

Top tissues by expression

98 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	91.31	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.95	gold quality
right uterine tube	UBERON:0001302	83.08	gold quality
fallopian tube	UBERON:0003889	82.95	gold quality
islet of Langerhans	UBERON:0000006	81.99	gold quality
pancreas	UBERON:0001264	68.58	gold quality
lymph node	UBERON:0000029	63.99	gold quality
duodenum	UBERON:0002114	62.08	gold quality
calcaneal tendon	UBERON:0003701	61.32	gold quality
gall bladder	UBERON:0002110	61.27	gold quality
adult mammalian kidney	UBERON:0000082	59.51	gold quality
kidney	UBERON:0002113	59.46	gold quality
prefrontal cortex	UBERON:0000451	59.44	gold quality
right hemisphere of cerebellum	UBERON:0014890	59.15	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.73	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.93	gold quality
cerebellar cortex	UBERON:0002129	57.70	gold quality
cerebellum	UBERON:0002037	57.69	gold quality
cerebellar hemisphere	UBERON:0002245	57.65	gold quality
bone marrow	UBERON:0002371	57.58	gold quality
corpus callosum	UBERON:0002336	57.52	gold quality
myometrium	UBERON:0001296	57.47	gold quality
blood	UBERON:0000178	57.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.81	gold quality
primary visual cortex	UBERON:0002436	55.77	gold quality
adrenal tissue	UBERON:0018303	55.73	gold quality
superior frontal gyrus	UBERON:0002661	55.43	gold quality
spleen	UBERON:0002106	55.18	gold quality
lung	UBERON:0002048	54.64	gold quality
adenohypophysis	UBERON:0002196	53.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.