GPR158-AS1

Summary

GPR158-AS1 (GPR158 antisense RNA 1, HGNC:44163) is a long non-coding RNA gene on chromosome 10p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44163
Approved symbol	GPR158-AS1
Name	GPR158 antisense RNA 1
Location	10p12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233642
Ensembl biotype	lncRNA
Entrez	100128811
RNAcentral	URS00000853F4 — lncRNA, 2433 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000449643, ENST00000808924, ENST00000808925, ENST00000808926, ENST00000808927

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449643 — 2 exons

Exon	Start	End
ENSE00004204184	25175676	25176707
ENSE00004204185	25158072	25159903

Expression profiles

Bgee: expression breadth broad, 31 present calls, max score 62.63.

Top tissues by expression

31 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
prostate gland	UBERON:0002367	62.63	silver quality
prefrontal cortex	UBERON:0000451	61.54	gold quality
putamen	UBERON:0001874	61.23	gold quality
nucleus accumbens	UBERON:0001882	59.72	gold quality
caudate nucleus	UBERON:0001873	59.22	gold quality
primary visual cortex	UBERON:0002436	58.65	gold quality
frontal cortex	UBERON:0001870	57.97	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	56.65	gold quality
Brodmann (1909) area 9	UBERON:0013540	56.31	gold quality
cerebral cortex	UBERON:0000956	55.61	gold quality
hypothalamus	UBERON:0001898	54.74	gold quality
brain	UBERON:0000955	54.63	gold quality
multicellular organism	UBERON:0000468	54.27	gold quality
superior frontal gyrus	UBERON:0002661	54.07	gold quality
right frontal lobe	UBERON:0002810	53.84	gold quality
anterior cingulate cortex	UBERON:0009835	53.18	gold quality
cerebellum	UBERON:0002037	52.59	gold quality
cerebellar cortex	UBERON:0002129	52.57	gold quality
cerebellar hemisphere	UBERON:0002245	52.56	gold quality
right hemisphere of cerebellum	UBERON:0014890	51.80	gold quality
substantia nigra	UBERON:0002038	51.69	gold quality
lymph node	UBERON:0000029	50.14	silver quality
skin of leg	UBERON:0001511	49.39	gold quality
islet of Langerhans	UBERON:0000006	49.38	gold quality
monocyte	CL:0000576	49.24	silver quality
Ammon’s horn	UBERON:0001954	48.49	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	48.24	gold quality
amygdala	UBERON:0001876	47.04	gold quality
blood	UBERON:0000178	45.09	silver quality
pituitary gland	UBERON:0000007	40.49	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.